4WD4
Crystal structure of human HO1 H25R
Summary for 4WD4
Entry DOI | 10.2210/pdb4wd4/pdb |
Descriptor | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | heme oxygenase, proximal histidine, heme coordination, site-directed mutagenesis, biliverdin biosensor, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 136114.85 |
Authors | Caaveiro, J.M.M.,Morante, K.,Sigala, P.,Tsumoto, K. (deposition date: 2014-09-06, release date: 2015-09-09, Last modification date: 2023-11-08) |
Primary citation | Sigala, P.A.,Morante, K.,Tsumoto, K.,Caaveiro, J.M.,Goldberg, D.E. In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis Biochemistry, 55:4836-4849, 2016 Cited by PubMed: 27490825DOI: 10.1021/acs.biochem.6b00562 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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