3VGO
Crystal structure of the N-terminal fragment of Cbl-b
Summary for 3VGO
Entry DOI | 10.2210/pdb3vgo/pdb |
Descriptor | E3 ubiquitin-protein ligase CBL-B (1 entity in total) |
Functional Keywords | merohedral twinning, e3 ligase, ligase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q13191 |
Total number of polymer chains | 3 |
Total formula weight | 136914.89 |
Authors | Kobashigawa, Y.,Noda, N.N.,Inagaki, F. (deposition date: 2011-08-18, release date: 2011-12-14, Last modification date: 2023-11-08) |
Primary citation | Kobashigawa, Y.,Tomitaka, A.,Kumeta, H.,Noda, N.N.,Yamaguchi, M.,Inagaki, F. Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108:20579-20584, 2011 Cited by PubMed: 22158902DOI: 10.1073/pnas.1110712108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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