Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle

Summary for 3V7A

Descriptor5B18 heavy chain, 5B18 kappa chain, Capsid
Functional Keywordsvirus, protein-fab complex, broadly-reactive antibody, immune system
Biological sourceHuman calicivirus
Total number of polymer chains6
Total molecular weight163978.02
Hansman, G.S.,Mclellan, J.S.,Kwong, P.D. (deposition date: 2011-12-20, release date: 2012-02-08, modification date: 2013-09-25)
Primary citation
Hansman, G.S.,Taylor, D.W.,McLellan, J.S.,Smith, T.J.,Georgiev, I.,Tame, J.R.,Park, S.Y.,Yamazaki, M.,Gondaira, F.,Miki, M.,Katayama, K.,Murata, K.,Kwong, P.D.
Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle.
J.Virol., 86:3635-3646, 2012
PubMed: 22278249
DOI: 10.1128/JVI.06868-11
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.277130.1%3.7%0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3v7a
no rotation
Molmil generated image of 3v7a
rotated about x axis by 90°
Molmil generated image of 3v7a
rotated about y axis by 90°
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