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3V7A

Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle

Summary for 3V7A

Related3ONU 
Descriptor5B18 heavy chain, 5B18 kappa chain, Capsid
Functional Keywordsvirus, Protein-Fab complex, broadly-reactive antibody, IMMUNE SYSTEM,IMMUNE SYSTEM
Biological sourceHuman calicivirus
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Total number of polymer chains6
Total molecular weight163978.02
Authors
Hansman, G.S.,Mclellan, J.S.,Kwong, P.D. (deposition date: 2011-12-20, release date: 2012-02-08, modification date: 2013-09-25)
Primary citation
Hansman, G.S.,Taylor, D.W.,McLellan, J.S.,Smith, T.J.,Georgiev, I.,Tame, J.R.,Park, S.Y.,Yamazaki, M.,Gondaira, F.,Miki, M.,Katayama, K.,Murata, K.,Kwong, P.D.
Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle.
J.Virol., 86:3635-3646, 2012
PubMed: 22278249
DOI: 10.1128/JVI.06868-11
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.297 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27650.1%3.7%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

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entries available on 2014-11-19
00:00 UTC / 09:00 JST