3RC0

Human SETD6 in complex with RelA Lys310 peptide

Summary for 3RC0

• Entry DOI: 10.2210/pdb3rc0/pdb
• Related: 3QXY
• Descriptor: N-lysine methyltransferase SETD6, Transcription factor p65 peptide, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: epigenetics, protein lysine monomethylation, mammalian nuclear factor kb (nf-kb), transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q8TBK2 Q04206
• Total number of polymer chains: 4
• Total formula weight: 107284.19

Authors

Chang, Y.,Levy, D.,Horton, J.R.,Peng, J.,Zhang, X.,Gozani, O.,Cheng, X. (deposition date: 2011-03-30, release date: 2011-05-25, Last modification date: 2023-09-13)

• Primary citation: Chang, Y.,Levy, D.,Horton, J.R.,Peng, J.,Zhang, X.,Gozani, O.,Cheng, X.; Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.; Nucleic Acids Res., 39:6380-6389, 2011; PubMed: 21515635; DOI: 10.1093/nar/gkr256

Experimental method

X-RAY DIFFRACTION (2.19 Å)