3PCS

Structure of EspG-PAK2 autoinhibitory Ialpha3 helix complex

Summary for 3PCS

• Entry DOI: 10.2210/pdb3pcs/pdb
• Related: 3PCR
• Descriptor: EspG, Serine/threonine-protein kinase PAK 2 (2 entities in total)
• Functional Keywords: bacterial effector, kinase, autoinhibitory ialpha3 helix, protein transport-transferase complex, protein transport/transferase
• Biological source: Escherichia coli; More
• Cellular location: Secreted : Q7DB50; Serine/threonine-protein kinase PAK 2: Cytoplasm. PAK-2p34: Nucleus: Q13177
• Total number of polymer chains: 8
• Total formula weight: 165814.14

Authors

Tomchick, D.R.,Alto, N.M.,Selyunin, A.S. (deposition date: 2010-10-21, release date: 2011-01-05, Last modification date: 2023-09-06)

• Primary citation: Selyunin, A.S.,Sutton, S.E.,Weigele, B.A.,Reddick, L.E.,Orchard, R.C.,Bresson, S.M.,Tomchick, D.R.,Alto, N.M.; The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.; Nature, 469:107-111, 2011; PubMed: 21170023; DOI: 10.1038/nature09593

Experimental method

X-RAY DIFFRACTION (2.86 Å)