3O7L
Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex
Summary for 3O7L
| Entry DOI | 10.2210/pdb3o7l/pdb |
| Related | 1ATP |
| Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, Cardiac phospholamban, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | protein kinase a, phospholamban, allostery, substrate recognition, conformational selection, intrinsically disordered proteins, membrane proteins, transferase |
| Biological source | Mus musculus (mouse) More |
| Cellular location | Cytoplasm (By similarity): P05132 P05132 Mitochondrion membrane; Single-pass membrane protein: P61014 |
| Total number of polymer chains | 3 |
| Total formula weight | 83633.60 |
| Authors | Cheng, C.Y.,Taylor, S.S. (deposition date: 2010-07-30, release date: 2010-10-06, Last modification date: 2023-09-06) |
| Primary citation | Masterson, L.R.,Cheng, C.,Yu, T.,Tonelli, M.,Kornev, A.,Taylor, S.S.,Veglia, G. Dynamics connect substrate recognition to catalysis in protein kinase A. Nat.Chem.Biol., 6:821-828, 2010 Cited by PubMed: 20890288DOI: 10.1038/nchembio.452 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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