3FSH

Crystal structure of the ubiquitin conjugating enzyme Ube2g2 bound to the G2BR domain of ubiquitin ligase gp78

Summary for 3FSH

Entry DOI	10.2210/pdb3fsh/pdb
Descriptor	Ubiquitin-conjugating enzyme E2 G2, Autocrine motility factor receptor, isoform 2 (3 entities in total)
Functional Keywords	protein-peptide complex, ligase, ubl conjugation pathway, alternative splicing, endoplasmic reticulum, membrane, metal-binding, phosphoprotein, polymorphism, receptor, transmembrane, zinc, zinc-finger
Biological source	Mus musculus (mouse) More
Cellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein: Q9UKV5
Total number of polymer chains	3
Total formula weight	41182.06
Authors	Tu, D.,Brunger, A.T. (deposition date: 2009-01-09, release date: 2009-02-10, Last modification date: 2023-09-06)
Primary citation	Li, W.,Tu, D.,Li, L.,Wollert, T.,Ghirlando, R.,Brunger, A.T.,Ye, Y. Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2. Proc.Natl.Acad.Sci.USA, 106:3722-3727, 2009 Cited by PubMed: 19223579 DOI: 10.1073/pnas.0808564106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.76 Å)

Structure validation