3F5F

Crystal structure of heparan sulfate 2-O-sulfotransferase from gallus gallus as a maltose binding protein fusion.

Summary for 3F5F

Entry DOI	10.2210/pdb3f5f/pdb
Related PRD ID	PRD_900001
Descriptor	Maltose-binding periplasmic protein, Heparan sulfate 2-O-sulfotransferase 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ADENOSINE-3'-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	maltose binding protein, fusion, heparan sulfate biosynthesis, sulfotransferase, glycoprotein, golgi apparatus, membrane, signal-anchor, transferase, transmembrane, periplasm, sugar transport, transport
Biological source	Escherichia coli K-12 (bantam,chickens) More
Cellular location	Golgi apparatus membrane ; Single-pass type II membrane protein : Q76KB1
Total number of polymer chains	1
Total formula weight	75055.83
Authors	Bethea, H.N.,Xu, D.,Liu, J.,Pedersen, L.C. (deposition date: 2008-11-03, release date: 2008-12-16, Last modification date: 2023-09-06)
Primary citation	Bethea, H.N.,Xu, D.,Liu, J.,Pedersen, L.C. Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis. Proc.Natl.Acad.Sci.USA, 105:18724-18729, 2008 Cited by PubMed: 19022906 DOI: 10.1073/pnas.0806975105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation