3DAB

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

Summary for 3DAB

Entry DOI	10.2210/pdb3dab/pdb
Related	1T4F 1YCR 2Z5S 2Z5T 3DAC
Descriptor	Mdm4 protein, Cellular tumor antigen p53 (3 entities in total)
Functional Keywords	mdmx, mdm4, hdmx, hdm4, mdm-4, mdm-x, mdm2, hdm2, p53, tumor, nucleus, oncogene, apoptosis, cell cycle, disease mutation, dna-binding, transcription
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	48328.12
Authors	Popowicz, G.M.,Czarna, A.,Holak, T.A. (deposition date: 2008-05-29, release date: 2008-09-02, Last modification date: 2023-11-01)
Primary citation	Popowicz, G.M.,Czarna, A.,Holak, T.A. Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain. Cell Cycle, 7:2441-2443, 2008 Cited by PubMed: 18677113 DOI: 10.4161/cc.6365 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation