3A9E

Crystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer ligand binding domains

Summary for 3A9E

• Entry DOI: 10.2210/pdb3a9e/pdb
• Related: 1DKF 1XDK
• Descriptor: Retinoic acid receptor RXR-alpha, Retinoic acid receptor alpha, 13-mer (LXXLL motif) from Nuclear receptor coactivator 2, ... (6 entities in total)
• Functional Keywords: transcription, nucleus, receptor, transcription regulation, structural genomics, spine2-complexes, structural proteomics in europe
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus: P28700 P10276 Q15596
• Total number of polymer chains: 3
• Total formula weight: 59549.15

Authors

Sato, Y.,Duclaud, S.,Peluso-Iltis, C.,Poussin, P.,Moras, D.,Rochel, N.,Structural Proteomics in Europe (SPINE) (deposition date: 2009-10-24, release date: 2010-10-06, Last modification date: 2023-11-01)

• Primary citation: Sato, Y.,Ramalanjaona, N.,Huet, T.,Potier, N.,Osz, J.,Antony, P.,Peluso-Iltis, C.,Poussin-Courmontagne, P.,Ennifar, E.,Mely, Y.,Dejaegere, A.,Moras, D.,Rochel, N.; The Phantom Effect of the Rexinoid LG100754: structural and functional insights; Plos One, 5:e15119-e15119, 2010; PubMed: 21152046; DOI: 10.1371/journal.pone.0015119

Experimental method

X-RAY DIFFRACTION (2.75 Å)