3ZWA

CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1 (RPMFE1) COMPLEXED WITH 3S-HYDROXY-HEXANOYL-COA

Summary for 3ZWA

• Entry DOI: 10.2210/pdb3zwa/pdb
• Related: 1ZCJ 2X58
• Descriptor: PEROXISOMAL BIFUNCTIONAL ENZYME, GLYCEROL, SULFATE ION, ... (5 entities in total)
• Functional Keywords: beta oxidation pathway, oxidoreductase, lipid metabolism, lyase, isomerase, peroxisome, fatty acid metabolism
• Biological source: RATTUS NORVEGICUS (NORWAY RAT)
• Cellular location: Peroxisome: P07896
• Total number of polymer chains: 2
• Total formula weight: 164186.43

Authors

Kasaragod, P.,Schmitz, W.,Hiltunen, J.K.,Wierenga, R.K. (deposition date: 2011-07-28, release date: 2012-08-08, Last modification date: 2023-12-20)

• Primary citation: Kasaragod, P.,Schmitz, W.,Kalervo Hiltunen, J.,Wierenga, R.K.; The Isomerase and Hydratase Reaction Mechanism of the Crotonase Active Site of the Multifunctional Enzyme (Type-1), as Deduced from Structures of Complexes with 3S-Hydroxy- Acyl-Coa.; FEBS J., 280:3160-, 2013; PubMed: 23351063; DOI: 10.1111/FEBS.12150

Experimental method

X-RAY DIFFRACTION (2.47 Å)