2XG3
Human galectin-3 in complex with a benzamido-N-acetyllactoseamine inhibitor
Summary for 2XG3
Entry DOI | 10.2210/pdb2xg3/pdb |
Related | 1A3K 1KJL 1KJR |
Descriptor | Galectin-3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | ige-binding protein, lectin, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16214.95 |
Authors | Diehl, C.,Engstrom, O.,Delaine, T.,Hakansson, M.,Genheden, S.,Modig, K.,Leffler, H.,Ryde, U.,Nilsson, U.,Akke, M. (deposition date: 2010-05-30, release date: 2010-10-13, Last modification date: 2024-05-01) |
Primary citation | Diehl, C.,Engstrom, O.,Delaine, T.,Hakansson, M.,Genheden, S.,Modig, K.,Leffler, H.,Ryde, U.,Nilsson, U.J.,Akke, M. Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3. J. Am. Chem. Soc., 132:14577-14589, 2010 Cited by PubMed: 20873837DOI: 10.1021/ja105852y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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