2WNG

complete extracellular structure of human signal regulatory protein (SIRP) alpha

Summary for 2WNG

Entry DOI	10.2210/pdb2wng/pdb
Related	2JJS 2JJT 2UV3
Descriptor	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	signal regulatory protein alpha, immunoglobulin superfamily, phosphoprotein, disulfide bond, paired receptor, alternative splicing, immunoglobulin domain, sirp, cd47, sirpa, membrane, sh3-binding, polymorphism, glycoprotein, transmembrane, cell adhesion
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	36425.54
Authors	Hatherley, D.,Graham, S.C.,Harlos, K.,Stuart, D.I.,Barclay, A.N. (deposition date: 2009-07-09, release date: 2009-07-21, Last modification date: 2023-12-13)
Primary citation	Hatherley, D.,Graham, S.C.,Harlos, K.,Stuart, D.I.,Barclay, A.N. Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution. J.Biol.Chem., 284:26613-, 2009 Cited by PubMed: 19628875 DOI: 10.1074/JBC.M109.017566 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.49 Å)

Structure validation