2VM6

Human Bcl2-A1 in complex with Bim-BH3 peptide

Summary for 2VM6

Entry DOI	10.2210/pdb2vm6/pdb
Related	2V6Q 2VM5
Descriptor	BCL-2-RELATED PROTEIN A1, BCL-2-LIKE PROTEIN 11, SULFATE ION, ... (4 entities in total)
Functional Keywords	b-cell lymphoma2, antiapoptotic, immune system, bim, bfl-1, bcl2a1, bcl-2a1, membrane, apoptosis
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	20460.18
Authors	Herman, M.D.,Lehtio, L.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,van den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2008-01-23, release date: 2008-02-05, Last modification date: 2019-09-25)
Primary citation	Herman, M.D.,Nyman, T.,Welin, M.,Lehtio, L.,Flodin, S.,Tresaugues, L.,Kotenyova, T.,Flores, A.,Nordlund, P. Completing the Family Portrait of the Anti- Apoptotic Bcl-2 Proteins: Crystal Structure of Human Bfl-1 in Complex with Bim. FEBS Lett., 582:3590-, 2008 Cited by PubMed: 18812174 DOI: 10.1016/J.FEBSLET.2008.09.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation