2QRV
Structure of Dnmt3a-Dnmt3L C-terminal domain complex
Summary for 2QRV
Entry DOI | 10.2210/pdb2qrv/pdb |
Related | 2PV0 2PVC |
Descriptor | DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5)-methyltransferase 3-like, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total) |
Functional Keywords | dna methyltransferase 3a (dnmt3a) and its regulatory factor, dna methyltransferase 3-like protein (dnmt3l), nucleus, s-adenosyl-l-methionine, transferase-transferase regulator complex, transferase/transferase regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9Y6K1 Nucleus (Probable): Q9UJW3 |
Total number of polymer chains | 8 |
Total formula weight | 244152.18 |
Authors | |
Primary citation | Jia, D.,Jurkowska, R.Z.,Zhang, X.,Jeltsch, A.,Cheng, X. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature, 449:248-251, 2007 Cited by PubMed: 17713477DOI: 10.1038/nature06146 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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