2QNA
Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65)
Summary for 2QNA
Entry DOI | 10.2210/pdb2qna/pdb |
Descriptor | Importin subunit beta-1, Snurportin-1, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nuclear transport, import of spliceosomal subunits, protein-protein interaction, heat-repeat protein, host-virus interaction, nucleus, protein transport, rna-binding, transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q14974 Nucleus : O95149 |
Total number of polymer chains | 2 |
Total formula weight | 92437.16 |
Authors | Wohlwend, D.,Strasser, A.,Dickmanns, A.,Ficner, R. (deposition date: 2007-07-18, release date: 2008-04-08, Last modification date: 2024-02-21) |
Primary citation | Wohlwend, D.,Strasser, A.,Dickmanns, A.,Ficner, R. Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374:1129-1138, 2007 Cited by PubMed: 18028944DOI: 10.1016/j.jmb.2007.09.065 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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