2EXM
Human CDK2 in complex with isopentenyladenine
Summary for 2EXM
Entry DOI | 10.2210/pdb2exm/pdb |
Descriptor | Cell division protein kinase 2, N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE (3 entities in total) |
Functional Keywords | typical protein kinase fold, ligand binding pocket between n-terminal and c-terminal domain, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941 |
Total number of polymer chains | 1 |
Total formula weight | 34179.73 |
Authors | Schulze-Gahmen, U. (deposition date: 2005-11-08, release date: 2005-12-27, Last modification date: 2024-02-14) |
Primary citation | Schulze-Gahmen, U.,Brandsen, J.,Jones, H.D.,Morgan, D.O.,Meijer, L.,Vesely, J.,Kim, S.H. Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine. Proteins, 22:378-391, 1995 Cited by PubMed: 7479711DOI: 10.1002/prot.340220408 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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