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2EXM

Human CDK2 in complex with isopentenyladenine

Summary for 2EXM
Entry DOI10.2210/pdb2exm/pdb
DescriptorCell division protein kinase 2, N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE (3 entities in total)
Functional Keywordstypical protein kinase fold, ligand binding pocket between n-terminal and c-terminal domain, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941
Total number of polymer chains1
Total formula weight34179.73
Authors
Schulze-Gahmen, U. (deposition date: 2005-11-08, release date: 2005-12-27, Last modification date: 2024-02-14)
Primary citationSchulze-Gahmen, U.,Brandsen, J.,Jones, H.D.,Morgan, D.O.,Meijer, L.,Vesely, J.,Kim, S.H.
Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine.
Proteins, 22:378-391, 1995
Cited by
PubMed: 7479711
DOI: 10.1002/prot.340220408
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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