2ACM

Solution structure of the SEA domain of human mucin 1 (MUC1)

Summary for 2ACM

Entry DOI	10.2210/pdb2acm/pdb
Descriptor	Mucin-1 (2 entities in total)
Functional Keywords	auto-catalytic proteolysis, structural protein
Biological source	Homo sapiens (human) More
Cellular location	Apical cell membrane; Single-pass type I membrane protein. Isoform 5: Secreted. Isoform 7: Secreted. Isoform 9: Secreted. Mucin-1 subunit beta: Cell membrane: Q16615 Q16615
Total number of polymer chains	2
Total formula weight	13879.25
Authors	Macao, B.,Johansson, D.G.A.,Hansson, G.C.,Hard, T. (deposition date: 2005-07-19, release date: 2006-01-17, Last modification date: 2022-03-09)
Primary citation	Macao, B.,Johansson, D.G.A.,Hansson, G.C.,Hard, T. Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin Nat.Struct.Mol.Biol., 13:71-76, 2006 Cited by PubMed: 16369486 DOI: 10.1038/nsmb1035 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation