1S1C

Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI

Summary for 1S1C

• Entry DOI: 10.2210/pdb1s1c/pdb
• Descriptor: Transforming protein RhoA, Rho-associated, coiled-coil containing protein kinase 1, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: coiled-coil, gtpase, rho kinase, rock, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side: P61586; Cytoplasm: Q13464
• Total number of polymer chains: 4
• Total formula weight: 59211.46

Authors

Dvorsky, R.,Blumenstein, L.,Vetter, I.R.,Ahmadian, M.R. (deposition date: 2004-01-06, release date: 2004-02-10, Last modification date: 2024-02-14)

• Primary citation: Dvorsky, R.,Blumenstein, L.,Vetter, I.R.,Ahmadian, M.R.; Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA.; J.Biol.Chem., 279:7098-7104, 2004; PubMed: 14660612; DOI: 10.1074/jbc.M311911200

Experimental method

X-RAY DIFFRACTION (2.6 Å)