1QWT

Auto-inhibitory interferon regulation factor-3 (IRF3) transactivation domain

Summary for 1QWT

Entry DOI	10.2210/pdb1qwt/pdb
Descriptor	Interferon regulatory factor 3, PHOSPHATE ION (3 entities in total)
Functional Keywords	dna binding protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q14653
Total number of polymer chains	2
Total formula weight	57079.37
Authors	Qin, B.Y. (deposition date: 2003-09-03, release date: 2003-10-14, Last modification date: 2011-07-13)
Primary citation	Qin, B.Y.,Liu, C.,Lam, S.S.,Srinath, H.,Delston, R.,Correia, J.J.,Derynck, R.,Lin, K. Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus induced phospho-activation Nat.Struct.Biol., 10:913-921, 2003 Cited by PubMed: 14555996 DOI: 10.1038/nsb1002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation