1MZF

Human Factor inhibiting HIF (FIH1) in Complex with 2-oxoglutarate

Summary for 1MZF

• Entry DOI: 10.2210/pdb1mzf/pdb
• Related: 1mze
• Descriptor: factor inhibiting HIF1, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
• Functional Keywords: beta-jellyroll, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Potential): Q9NWT6
• Total number of polymer chains: 1
• Total formula weight: 40658.35

Authors

Dann III, C.E.,Bruick, R.K.,Deisenhofer, J. (deposition date: 2002-10-07, release date: 2002-11-20, Last modification date: 2024-04-03)

• Primary citation: Dann III, C.E.,Bruick, R.K.,Deisenhofer, J.; Structure of Factor-Inhibiting Hypoxia-Inducible Factor 1: An Asparaginyl Hydroxylase Involved in the Hypoxic Response Pathway.; Proc.Natl.Acad.Sci.USA, 99:15351-15356, 2002; PubMed: 12432100; DOI: 10.1073/pnas.202614999

Experimental method

X-RAY DIFFRACTION (2.4 Å)