Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids

Summary for 1LV2

DescriptorHepatocyte nuclear factor 4-gamma
Functional Keywordsdiabetes, fatty acids, HNF4, MODY, nuclear receptor, transcription factor, TRANSCRIPTION,TRANSCRIPTION
Biological sourceHomo sapiens (human)
Cellular locationNucleus (By similarity) Q14541
Total number of polymer chains1
Total molecular weight26111.52
Wisely, B.,Miller, A.B.,Davis, R.G.,Spitzer, T.,Shearer, B.,Moore, J.T.,Johnson, R.,Sefler, A.,Willson, T.M.,Williams, S.P. (deposition date: 2002-05-24, release date: 2002-12-18, modification date: 2011-11-16)
Primary citation
Wisely, G.B.,Miller, A.B.,Davis, R.G.,Jr Thornquest, A.D.,Johnson, R.,Spitzer, T.,Sefler, A.,Shearer, B.,Moore, J.T.,Willson, T.M.,Williams, S.P.
Hepatocyte Nuclear Factor 4 Is a Transcription Factor that Constitutively Binds Fatty Acids.
Structure, 10:1225-1234, 2002
PubMed: 12220494
DOI: 10.1016/S0969-2126(02)00829-8
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers272.3%9.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

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