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Crystal structure of IL-17F

Summary for 1JPY

Descriptorinterleukin 17F
Functional Keywordscystine-knot, cytokine, t-cell derived, dimer, IMMUNE SYSTEM,IMMUNE SYSTEM
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total molecular weight62729.99
Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A. (deposition date: 2001-08-03, release date: 2001-09-28, modification date: 2011-07-13)
Primary citation
Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.P.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.F.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A.
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20:5332-5341, 2001
PubMed: 11574464
DOI: 10.1093/emboj/20.19.5332
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.279201.3%9.5%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

no rotation
rotated about x axis by 90°
rotated about y axis by 90°
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entries available on 2015-07-01
00:00 UTC / 09:00 JST