1JPY

Crystal structure of IL-17F

Summary for 1JPY

Descriptorinterleukin 17F
Functional Keywordscystine-knot, cytokine, t-cell derived, dimer, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total molecular weight62729.99
Authors
Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A. (deposition date: 2001-08-03, release date: 2001-09-28, modification date: 2011-07-13)
Primary citation
Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.P.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.F.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A.
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20:5332-5341, 2001
PubMed: 11574464
DOI: 10.1093/emboj/20.19.5332
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.85 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.280201.3%9.5%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1jpy
no rotation
Molmil generated image of 1jpy
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Molmil generated image of 1jpy
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 1jpy
no rotation
Molmil generated image of 1jpy
rotated about x axis by 90°
Molmil generated image of 1jpy
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1jpy.pdb1.gz [41.71 KB])
Coordinate files for Biological unit (1jpy.pdb2.gz [40.85 KB])
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