1CVS
CRYSTAL STRUCTURE OF A DIMERIC FGF2-FGFR1 COMPLEX
Summary for 1CVS
Entry DOI | 10.2210/pdb1cvs/pdb |
Descriptor | FIBROBLAST GROWTH FACTOR 2, FIBROBLAST GROWTH FACTOR RECEPTOR 1, SULFATE ION (3 entities in total) |
Functional Keywords | fgf, fgfr, immunoglobulin-like, signal transduction, dimerization, growth factor-growth factor receptor complex, growth factor/growth factor receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P11362 |
Total number of polymer chains | 4 |
Total formula weight | 81154.54 |
Authors | Plotnikov, A.N.,Schlessinger, J.,Hubbard, S.R.,Mohammadi, M. (deposition date: 1999-08-24, release date: 2000-01-28, Last modification date: 2024-04-03) |
Primary citation | Plotnikov, A.N.,Schlessinger, J.,Hubbard, S.R.,Mohammadi, M. Structural basis for FGF receptor dimerization and activation. Cell(Cambridge,Mass.), 98:641-650, 1999 Cited by PubMed: 10490103DOI: 10.1016/S0092-8674(00)80051-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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