7LUV
Cryo-EM structure of the yeast THO-Sub2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | THO complex subunit HPR1 | polymer | 603 | 71126.2 | 1 | UniProt (P17629) Pfam (PF11957) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Hyperrecombination protein 1 |
| 2 | B | THO complex subunit THP2 | polymer | 261 | 30340.3 | 1 | UniProt (O13539) Pfam (PF09432) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
| 3 | C | THO complex subunit 2 | polymer | 1262 | 138881.5 | 1 | UniProt (P53552) Pfam (PF16134) Pfam (PF11732) Pfam (PF11262) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Low dye-binding protein 5,THO complex subunit RLR1,Zinc-regulated gene 13 protein |
| 4 | D | THO complex subunit MFT1 | polymer | 256 | 29467.5 | 1 | UniProt (P33441) Pfam (PF05615) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Mitochondrial fusion target protein 1 |
| 5 | E | Tex1 | polymer | 385 | 41248.7 | 1 | Pfam (PF00400) UniProt (by SIFTS) (A0A0L8RC19) UniProt (by SIFTS) (Q1ESZ7) In PDB | Saccharomyces bayanus | |
| 6 | M | ATP-dependent RNA helicase SUB2 | polymer | 446 | 50375.9 | 1 | UniProt (Q07478) Pfam (PF00271) Pfam (PF00270) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Suppressor of BRR1 protein 2 |
Sequence modifications
C: 1 - 7449 (UniProt: P53552)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Unk 37 | Trp 37 | conflict |
| Unk 38 | Pro 38 | conflict |
| Unk 39 | Glu 39 | conflict |
| Unk 40 | Arg 40 | conflict |
| Unk 41 | Ser 41 | conflict |
| Unk 42 | Lys 42 | conflict |
| Unk 43 | Thr 43 | conflict |
| Unk 44 | Leu 44 | conflict |
| Unk 45 | Cys 45 | conflict |
| Unk 46 | Ser 46 | conflict |
| Unk 47 | Asp 47 | conflict |
| Unk 48 | Phe 48 | conflict |
| Unk 49 | Thr 49 | conflict |
| Unk 50 | Ala 50 | conflict |
| Unk 51 | Leu 51 | conflict |
| Unk 75 | Asn 75 | conflict |
| Unk 76 | Asp 76 | conflict |
| Unk 77 | Glu 77 | conflict |
| Unk 78 | Asn 78 | conflict |
| Unk 79 | Ser 79 | conflict |
| Unk 80 | Pro 80 | conflict |
| Unk 81 | Leu 81 | conflict |
| Unk 82 | Lys 82 | conflict |
| Unk 83 | Leu 83 | conflict |
| Unk 84 | Ser 84 | conflict |
| Unk 85 | Asp 85 | conflict |
| Unk 86 | Val 86 | conflict |
| Unk 87 | Ala 87 | conflict |
| Unk 88 | Ser 88 | conflict |
| Unk 89 | Phe 89 | conflict |
| Unk 90 | Thr 90 | conflict |
| Unk 91 | Asn 91 | conflict |
| Unk 92 | Glu 92 | conflict |
| Unk 93 | Leu 93 | conflict |
| Unk 94 | Val 94 | conflict |
| Unk 95 | Asn 95 | conflict |
| Unk 96 | His 96 | conflict |
| Unk 97 | Glu 97 | conflict |
| Unk 98 | Arg 98 | conflict |
| Unk 99 | Gln 99 | conflict |
| Unk 100 | Val 100 | conflict |
| Unk 101 | Ser 101 | conflict |
| Unk 102 | Gln 102 | conflict |
| Unk 103 | Ala 103 | conflict |
| Unk 104 | Ser 104 | conflict |
| Unk 105 | Ile 105 | conflict |
| Unk 106 | Val 106 | conflict |
| Unk 107 | Gly 107 | conflict |
| Unk 108 | Lys 108 | conflict |
| Unk 109 | Met 109 | conflict |
| Unk 110 | Phe 110 | conflict |
| Unk 111 | Ile 111 | conflict |
| Unk 112 | Ala 112 | conflict |
| Unk 113 | Val 113 | conflict |
| Unk 114 | Ser 114 | conflict |
| Unk 115 | Ser 115 | conflict |
| Unk 116 | Thr 116 | conflict |
| Unk 117 | Val 117 | conflict |
| Unk 118 | Pro 118 | conflict |
| Unk 119 | Asn 119 | conflict |
| Unk 120 | Ile 120 | conflict |
| Unk 121 | Asn 121 | conflict |
| Unk 122 | Asp 122 | conflict |
| Unk 6941 | Gln 914 | conflict |
| Unk 6942 | Leu 915 | conflict |
| Unk 6943 | Asn 916 | conflict |
| Unk 6944 | Ser 917 | conflict |
| Unk 6945 | Asn 918 | conflict |
| Unk 6946 | Glu 919 | conflict |
| Unk 6947 | Asn 920 | conflict |
| Unk 6948 | Phe 921 | conflict |
| Unk 6949 | Ser 922 | conflict |
| Unk 6950 | Ile 923 | conflict |
| Unk 6951 | Asp 924 | conflict |
| Unk 6991 | Glu 925 | conflict |
| Unk 6992 | Leu 926 | conflict |
| Unk 6993 | Ile 927 | conflict |
| Unk 6994 | Glu 928 | conflict |
| Unk 6995 | Gly 929 | conflict |
| Unk 6996 | Ala 930 | conflict |
| Unk 6997 | Glu 931 | conflict |
| Unk 6998 | Phe 932 | conflict |
| Unk 6999 | Ser 933 | conflict |
| Unk 7000 | Asp 934 | conflict |
| Unk 7001 | Val 935 | conflict |
| Unk 7002 | Asp 936 | conflict |
| Unk 7003 | Leu 937 | conflict |
| Unk 7004 | Thr 938 | conflict |
| Unk 7005 | Lys 939 | conflict |
| Unk 7006 | Ile 940 | conflict |
| Unk 7007 | Ser 941 | conflict |
| Unk 7008 | Lys 942 | conflict |
| Unk 7009 | Asp 943 | conflict |
| Unk 7010 | Leu 944 | conflict |
| Unk 7011 | Phe 945 | conflict |
| Unk 7012 | Thr 946 | conflict |
| Unk 7028 | Thr 947 | conflict |
| Unk 7029 | Phe 948 | conflict |
| Unk 7030 | Trp 949 | conflict |
| Unk 7031 | Arg 950 | conflict |
| Unk 7032 | Leu 951 | conflict |
| Unk 7033 | Ser 952 | conflict |
| Unk 7034 | Leu 953 | conflict |
| Unk 7035 | Tyr 954 | conflict |
| Unk 7036 | Asp 955 | conflict |
| Unk 7037 | Ile 956 | conflict |
| Unk 7038 | His 957 | conflict |
| Unk 7039 | Phe 958 | conflict |
| Unk 7040 | Asp 959 | conflict |
| Unk 7047 | Lys 960 | conflict |
| Unk 7048 | Ser 961 | conflict |
| Unk 7049 | Leu 962 | conflict |
| Unk 7050 | Tyr 963 | conflict |
| Unk 7051 | Asp 964 | conflict |
| Unk 7052 | Glu 965 | conflict |
| Unk 7053 | Arg 966 | conflict |
| Unk 7054 | Lys 967 | conflict |
| Unk 7055 | Asn 968 | conflict |
| Unk 7056 | Ala 969 | conflict |
| Unk 7057 | Leu 970 | conflict |
| Unk 7058 | Ser 971 | conflict |
| Unk 7059 | Gly 972 | conflict |
| Unk 7060 | Glu 973 | conflict |
| Unk 7131 | Asn 974 | conflict |
| Unk 7132 | Thr 975 | conflict |
| Unk 7133 | Gly 976 | conflict |
| Unk 7134 | His 977 | conflict |
| Unk 7135 | Met 978 | conflict |
| Unk 7136 | Ser 979 | conflict |
| Unk 7137 | Asn 980 | conflict |
| Unk 7138 | Arg 981 | conflict |
| Unk 7139 | Lys 982 | conflict |
| Unk 7140 | Lys 983 | conflict |
| Unk 7141 | His 984 | conflict |
| Unk 7142 | Leu 985 | conflict |
| Unk 7143 | Ile 986 | conflict |
| Unk 7144 | Gln 987 | conflict |
| Unk 7145 | Asn 988 | conflict |
| Unk 7146 | Gln 989 | conflict |
| Unk 7147 | Ile 990 | conflict |
| Unk 7148 | Lys 991 | conflict |
| Unk 7149 | Asp 992 | conflict |
| Unk 7150 | Ile 993 | conflict |
| Unk 7159 | Leu 994 | conflict |
| Unk 7160 | Val 995 | conflict |
| Unk 7161 | Thr 996 | conflict |
| Unk 7162 | Gly 997 | conflict |
| Unk 7163 | Ile 998 | conflict |
| Unk 7164 | Ser 999 | conflict |
| Unk 7165 | His 1000 | conflict |
| Unk 7166 | Gln 1001 | conflict |
| Unk 7167 | Arg 1002 | conflict |
| Unk 7168 | Ala 1003 | conflict |
| Unk 7169 | Phe 1004 | conflict |
| Unk 7170 | Lys 1005 | conflict |
| Unk 7171 | Lys 1006 | conflict |
| Unk 7172 | Thr 1007 | conflict |
| Unk 7173 | Ser 1008 | conflict |
| Unk 7174 | Glu 1009 | conflict |
| Unk 7175 | Phe 1010 | conflict |
| Unk 7176 | Ile 1011 | conflict |
| Unk 7180 | Ser 1012 | conflict |
| Unk 7181 | Glu 1013 | conflict |
| Unk 7182 | Lys 1014 | conflict |
| Unk 7183 | Ser 1015 | conflict |
| Unk 7184 | Asn 1016 | conflict |
| Unk 7185 | Val 1017 | conflict |
| Unk 7186 | Trp 1018 | conflict |
| Unk 7187 | Asn 1019 | conflict |
| Unk 7188 | Lys 1020 | conflict |
| Unk 7189 | Asp 1021 | conflict |
| Unk 7190 | Cys 1022 | conflict |
| Unk 7191 | Gly 1023 | conflict |
| Unk 7192 | Glu 1024 | conflict |
| Unk 7193 | Asp 1025 | conflict |
| Unk 7194 | Gln 1026 | conflict |
| Unk 7195 | Ile 1027 | conflict |
| Unk 7196 | Lys 1028 | conflict |
| Unk 7197 | Ile 1029 | conflict |
| Unk 7198 | Phe 1030 | conflict |
| Unk 7199 | Leu 1031 | conflict |
| Unk 7200 | Gln 1032 | conflict |
| Unk 7201 | Asn 1033 | conflict |
| Unk 7211 | Cys 1034 | conflict |
| Unk 7212 | Val 1035 | conflict |
| Unk 7213 | Val 1036 | conflict |
| Unk 7214 | Pro 1037 | conflict |
| Unk 7215 | Arg 1038 | conflict |
| Unk 7216 | Val 1039 | conflict |
| Unk 7217 | Leu 1040 | conflict |
| Unk 7218 | Phe 1041 | conflict |
| Unk 7219 | Ser 1042 | conflict |
| Unk 7220 | Pro 1043 | conflict |
| Unk 7221 | Ser 1044 | conflict |
| Unk 7222 | Asp 1045 | conflict |
| Unk 7223 | Ala 1046 | conflict |
| Unk 7224 | Leu 1047 | conflict |
| Unk 7225 | Phe 1048 | conflict |
| Unk 7234 | Ser 1049 | conflict |
| Unk 7235 | Ser 1050 | conflict |
| Unk 7236 | Phe 1051 | conflict |
| Unk 7237 | Phe 1052 | conflict |
| Unk 7238 | Ile 1053 | conflict |
| Unk 7239 | Phe 1054 | conflict |
| Unk 7240 | Met 1055 | conflict |
| Unk 7241 | Ala 1056 | conflict |
| Unk 7242 | Phe 1057 | conflict |
| Unk 7243 | Arg 1058 | conflict |
| Unk 7244 | Thr 1059 | conflict |
| Unk 7245 | Glu 1060 | conflict |
| Unk 7246 | Asn 1061 | conflict |
| Unk 7247 | Leu 1062 | conflict |
| Unk 7248 | Met 1063 | conflict |
| Unk 7256 | Ser 1064 | conflict |
| Unk 7257 | Ile 1065 | conflict |
| Unk 7258 | Leu 1066 | conflict |
| Unk 7259 | Asn 1067 | conflict |
| Unk 7260 | Thr 1068 | conflict |
| Unk 7261 | Cys 1069 | conflict |
| Unk 7262 | Ile 1070 | conflict |
| Unk 7263 | Thr 1071 | conflict |
| Unk 7264 | Ser 1072 | conflict |
| Unk 7265 | Asn 1073 | conflict |
| Unk 7266 | Ile 1074 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 361439.9 | |
| All* | Total formula weight | 361439.9 |
