6FWB

Crystal structure of Mat2A at 1.79 Angstron resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D	S-adenosylmethionine synthase isoform type-2	polymer	410	45527.6	4	UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB	Homo sapiens (Human)	AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II
2	D, B, A	SULFATE ION	non-polymer		96.1	19	Chemie (SO4)
3	D, B, A, C	TETRAETHYLENE GLYCOL	non-polymer		194.2	7	Chemie (PG4)
4	B	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5	D, A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6		water	water		18.0	521	Chemie (HOH)

Sequence modifications

B, A, C, D: 1 - 394 (UniProt: P31153)

PDB	External Database	Details
Met -15	-	initiating methionine
Ala -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	182110.3
Non-Polymers*	Number of molecules	29
	Total formula weight	3392.0
All*	Total formula weight	185502.3

*Water molecules are not included.