5OKF

CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with self-bound phosphopeptides

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	14-3-3 protein sigma,Heat shock protein beta-6	polymer	246	27508.9	4	UniProt (P31947) UniProt (O14558) Pfam (PF00244)	Homo sapiens (Human)	Epithelial cell marker protein 1,Stratifin,HspB6,Heat shock 20 kDa-like protein p20
2	E, F, G, H, I... (A, B, C, D)	CADMIUM ION	non-polymer		112.4	17	Chemie (CD)
3	V, W, X, Y (A, B, C, D)	water	water		18.0	22	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 231 (UniProt: P31947)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
His 0	-	expression tag
Ala 75	Glu 75	engineered mutation
Ala 76	Glu 76	engineered mutation
Ala 77	Lys 77	engineered mutation
Gly 232	-	linker
Ser 233	-	linker
Gly 234	-	linker
Ser 235	-	linker

A, B, C, D: 236 - 243 (UniProt: O14558)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110035.6
Non-Polymers*	Number of molecules	17
	Total formula weight	1911.0
All*	Total formula weight	111946.6

*Water molecules are not included.