4RZF
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Nuclear receptor subfamily 4 group A member 1 | polymer | 256 | 28713.2 | 2 | UniProt (P22736) Pfam (PF00104) | Homo sapiens (human) | Early response protein NAK1, Nuclear hormone receptor NUR/77, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3 |
| 2 | C, D, E (B, A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | F, G (B, A) | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
B, A: 20 - 267 (UniProt: P22736)
| PDB | External Database | Details |
|---|---|---|
| Trp 110 | Ser 441 | engineered mutation |
| Leu 268 | - | expression tag |
| Glu 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57426.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 57702.8 |
