4RZF

Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Nuclear receptor subfamily 4 group A member 1	polymer	256	28713.2	2	UniProt (P22736) Pfam (PF00104) In PDB	Homo sapiens (human)	Early response protein NAK1, Nuclear hormone receptor NUR/77, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3
2	B, A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
3		water	water		18.0	342	Chemie (HOH)

Sequence modifications

B, A: 20 - 267 (UniProt: P22736)

PDB	External Database	Details
Trp 110	Ser 441	engineered mutation
Leu 268	-	expression tag
Glu 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57426.5
Non-Polymers*	Number of molecules	3
	Total formula weight	276.3
All*	Total formula weight	57702.8

*Water molecules are not included.