4G2K
Crystal structure of the Marburg Virus GP2 ectodomain in its post-fusion conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | General control protein GCN4, Envelope glycoprotein GP2 chimera | polymer | 125 | 14691.9 | 3 | UniProt (P03069) UniProt (P35254) Pfam (PF07716) In PDB | Saccharomyces cerevisiae (yeast Marburg virus) | Amino acid biosynthesis regulatory protein, virion spike glycoprotein |
2 | A, C | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
A, B, C: 524 - 553 (UniProt: P03069)
A, B, C: 554 - 633 (UniProt: P35254)
PDB | External Database | Details |
---|---|---|
Met 509 | - | expression tag |
His 510 | - | expression tag |
His 511 | - | expression tag |
His 512 | - | expression tag |
His 513 | - | expression tag |
His 514 | - | expression tag |
His 515 | - | expression tag |
Glu 516 | - | expression tag |
Asn 517 | - | expression tag |
Leu 518 | - | expression tag |
Tyr 519 | - | expression tag |
Phe 520 | - | expression tag |
Gln 521 | - | expression tag |
Gly 522 | - | expression tag |
Asn 523 | - | expression tag |
Ile 527 | Leu 253 | engineered mutation |
Ile 531 | Val 257 | engineered mutation |
Ile 534 | Leu 260 | engineered mutation |
Ile 538 | Asn 264 | engineered mutation |
Ile 541 | Leu 267 | engineered mutation |
Ile 545 | Val 271 | engineered mutation |
Ile 548 | Leu 274 | engineered mutation |
Ile 552 | Val 278 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 557 | Cys 557 | engineered mutation |
Ser 610 | Cys 610 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 44075.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 219.6 | |
All* | Total formula weight | 44295.3 |