3MBG

Crystal Structure of Human Augmenter of Liver Regeneration (ALR)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	FAD-linked sulfhydryl oxidase ALR	polymer	139	16499.5	3	UniProt (P55789) Pfam (PF04777) In PDB	Homo sapiens (human)	Augmenter of liver regeneration, hERV1, Hepatopoietin
2	A, B, C	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	3	Chemie (FAD)
3	C, A, B	ZINC ION	non-polymer		65.4	10	Chemie (ZN)
4	A, B, C	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
5	C, A, B	ACETATE ION	non-polymer		59.0	11	Chemie (ACT)
6		water	water		18.0	291	Chemie (HOH)

Sequence modifications

A, B, C: 81 - 205 (UniProt: P55789)

PDB	External Database	Details
Met 67	-	expression tag
Gly 68	-	expression tag
Gly 69	-	expression tag
Ser 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
His 74	-	expression tag
His 75	-	expression tag
His 76	-	expression tag
Gly 77	-	expression tag
Met 78	-	expression tag
Ala 79	-	expression tag
Ser 80	-	expression tag
Ala 154	Cys 154	engineered mutation
Ala 165	Cys 165	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	49498.4
Non-Polymers*	Number of molecules	28
	Total formula weight	3752.2
All*	Total formula weight	53250.6

*Water molecules are not included.