3ET9

Crystal structure of the engineered neutralizing antibody 1H

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	F	Antibody 1H light chain and antibody 1H heavy chain linked with a synthetic (GGGGS)4 linker	polymer	252	26758.6	1		Mus musculus (Mouse)
2		water	water		18.0	16	Chemie (HOH)

Sequence modifications

F: 1 - 108 (PDB: 3ET9)

PDB	External Database	Details
Met -4	-	expression tag
Ala -3	-	expression tag
Asp -2	-	expression tag
Tyr -1	-	expression tag
Lys 0	-	expression tag
Leu 55	Gln 55	engineered mutation
Pro 56	Ser 56	engineered mutation
Arg 107	Lys 107	engineered mutation

F: 1001 - 1113 (PDB: 3ET9)

PDB	External Database	Details
Gly 109	-	linker
Gly 110	-	linker
Gly 111	-	linker
Gly 112	-	linker
Ser 113	-	linker
Gly 114	-	linker
Gly 115	-	linker
Gly 116	-	linker
Gly 117	-	linker
Ser 118	-	linker
Gly 119	-	linker
Gly 120	-	linker
Gly 121	-	linker
Gly 122	-	linker
Ser 123	-	linker
Gly 124	-	linker
Gly 125	-	linker
Gly 126	-	linker
Gly 127	-	linker
Ser 128	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26758.6
All*	Total formula weight	26758.6

*Water molecules are not included.