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1K6O
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BU of 1k6o by Molmil
Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex
Descriptor: 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ...
Authors:Mo, Y, Ho, W, Johnston, K, Marmorstein, R.
Deposit date:2001-10-16
Release date:2002-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
J.Mol.Biol., 314, 2001
1HBX
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BU of 1hbx by Molmil
Ternary Complex of SAP-1 and SRF with specific SRE DNA
Descriptor: 5'-D(*CP*AP*CP*AP*CP*CP*GP*GP*AP*AP*GP*TP*CP* CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*CP*AP*T)-3', 5'-D(*GP*AP*TP*GP*GP*CP*CP*TP*AP*AP*TP*TP*AP* GP*GP*AP*CP*TP*TP*CP*CP*GP*GP*TP*G)-3', ETS-DOMAIN PROTEIN ELK-4, ...
Authors:Hassler, M, Richmond, T.J.
Deposit date:2001-04-20
Release date:2001-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The B-Box Dominates Sap-1/Srf Interactions in the Structure of the Ternary Complex
Embo J., 20, 2001
1SRS
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BU of 1srs by Molmil
SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA
Descriptor: DNA (5'-D(*CP*CP*(5IU)P*TP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*TP*GP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*A P*AP*G)-3'), PROTEIN (SERUM RESPONSE FACTOR (SRF))
Authors:Pellegrini, L, Tan, S, Richmond, T.J.
Deposit date:1995-07-28
Release date:1995-07-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of serum response factor core bound to DNA.
Nature, 376, 1995
1BC7
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BU of 1bc7 by Molmil
SERUM RESPONSE FACTOR ACCESSORY PROTEIN 1A (SAP-1)/DNA COMPLEX
Descriptor: DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*AP*GP*GP*AP*TP*GP*TP*G)-3'), PROTEIN (ETS-DOMAIN PROTEIN)
Authors:Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
Deposit date:1998-05-05
Release date:1999-01-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2, 1998
2HI3
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BU of 2hi3 by Molmil
Solution structure of the homeodomain-only protein HOP
Descriptor: Homeodomain-only protein
Authors:Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W.
Deposit date:2006-06-28
Release date:2007-01-02
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Analysis of the structure and function of the transcriptional coregulator HOP
Biochemistry, 45, 2006
1BC8
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BU of 1bc8 by Molmil
STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS
Descriptor: DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ...
Authors:Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
Deposit date:1998-05-05
Release date:1998-12-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2, 1998
7Y7A
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BU of 7y7a by Molmil
In situ double-PBS-PSII-PSI-LHCs megacomplex from Porphyridium purpureum.
Descriptor: (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (2S)-2,3-dihydroxypropyl octadecanoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
Authors:You, X, Zhang, X, Cheng, J, Xiao, Y.N, Sun, S, Sui, S.F.
Deposit date:2022-06-22
Release date:2023-02-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex.
Nature, 616, 2023
4V6F
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BU of 4v6f by Molmil
Elongation complex of the 70S ribosome with three tRNAs and mRNA.
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 23S RRNA, ...
Authors:Jenner, L.B, Yusupova, G, Yusupov, M.
Deposit date:2009-07-09
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
3TPM
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BU of 3tpm by Molmil
Crystal structure of MAL RPEL domain in complex with importin-alpha
Descriptor: Importin subunit alpha-2, MAL
Authors:Hirano, H, Matsuura, Y.
Deposit date:2011-09-08
Release date:2011-10-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL
Biochem.Biophys.Res.Commun., 414, 2011
3TPQ
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BU of 3tpq by Molmil
Crystal structure of wild-type MAL RPEL domain in complex with five G-actins
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Hirano, H, Matsuura, Y.
Deposit date:2011-09-08
Release date:2011-10-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL
Biochem.Biophys.Res.Commun., 414, 2011
3TPO
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BU of 3tpo by Molmil
Crystal structure of D192A/E396A mutant of mouse importin alpha2
Descriptor: Importin subunit alpha-2
Authors:Hirano, H, Matsuura, Y.
Deposit date:2011-09-08
Release date:2011-10-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL
Biochem.Biophys.Res.Commun., 414, 2011
1EGW
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BU of 1egw by Molmil
CRYSTAL STRUCTURE OF MEF2A CORE BOUND TO DNA
Descriptor: DNA (5'-D(*AP*AP*AP*GP*CP*TP*AP*TP*TP*AP*TP*TP*AP*GP*CP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*GP*CP*TP*AP*AP*TP*AP*AP*TP*AP*GP*CP*TP*T)-3'), MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, ...
Authors:Santelli, E, Richmond, T.J.
Deposit date:2000-02-17
Release date:2000-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of MEF2A core bound to DNA at 1.5 A resolution.
J.Mol.Biol., 297, 2000
1C7U
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BU of 1c7u by Molmil
Complex of the DNA binding core domain of the transcription factor MEF2A with a 20mer oligonucleotide
Descriptor: 5'-D(*CP*TP*CP*GP*GP*CP*TP*AP*TP*TP*AP*AP*TP*AP*GP*CP*CP*GP*AP*G)-3', MYOCYTE-SPECIFIC ENHANCER FACTOR 2A, C4 FORM
Authors:Clore, G.M, Huang, K.
Deposit date:2000-03-17
Release date:2000-03-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors
Embo J., 19, 2000
1DUX
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BU of 1dux by Molmil
ELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION
Descriptor: DNA (5'-D(*AP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*T)-3'), ETS-DOMAIN PROTEIN ELK-1
Authors:Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
Deposit date:2000-01-19
Release date:2000-04-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the elk-1-DNA complex reveals how DNA-distal residues affect ETS domain recognition of DNA.
Nat.Struct.Biol., 7, 2000
2D9B
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BU of 2d9b by Molmil
Solution Structure of RSGI RUH-052, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I
Authors:Doi-Katayama, Y, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-09
Release date:2006-06-09
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-052, a GTF2I domain in human cDNA
To be Published
2DN4
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BU of 2dn4 by Molmil
Solution Structure of RSGI RUH-060, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I
Authors:Doi-Katayama, Y, Hirota, H, Suetake, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-25
Release date:2006-10-25
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-060, a GTF2I domain in human cDNA
To be published
2ED2
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BU of 2ed2 by Molmil
Solution Structure of RSGI RUH-069, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I
Authors:Doi-Katayama, Y, Hirota, H, Izumi, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-14
Release date:2007-08-14
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-069, a GTF2I domain in human cDNA
To be published
2EJE
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BU of 2eje by Molmil
Solution Structure of RSGI RUH-071, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I
Authors:Doi-Katayama, Y, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2007-09-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-071, a GTF2I domain in human cDNA
To be Published
6YX0
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BU of 6yx0 by Molmil
Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid
Descriptor: 4-[[2-(4-oxidanylidenebutanoyl)hydrazinyl]methyl]benzoic acid, PWQ-THR-ARG-LEU, SH3 and multiple ankyrin repeat domains protein 1
Authors:Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J.
Deposit date:2020-04-30
Release date:2021-01-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.
Chem Sci, 12, 2021
6YWZ
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BU of 6ywz by Molmil
Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid
Descriptor: 2-[(~{E})-(4-oxidanylidenebutanoylhydrazinylidene)methyl]benzoic acid, ARGININE, DI(HYDROXYETHYL)ETHER, ...
Authors:Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Lian, L.J, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J.
Deposit date:2020-04-30
Release date:2021-01-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.
Chem Sci, 12, 2021
6YX2
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BU of 6yx2 by Molmil
Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid
Descriptor: 4-[[(~{E})-5-oxidanylidenepentanoyldiazenyl]methyl]benzoic acid, PWW-THR-ARG-LEU, SH3 and multiple ankyrin repeat domains protein 1
Authors:Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Lian, L.J, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J.
Deposit date:2020-04-30
Release date:2021-01-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.
Chem Sci, 12, 2021
6YX1
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BU of 6yx1 by Molmil
Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid
Descriptor: 2-[[2-(5-oxidanylidenepentanoyl)hydrazinyl]methyl]benzoic acid, ARGININE, LEUCINE, ...
Authors:Hegedus, Z, Hobor, F, Shoemark, D.K, Celis, S, Lian, L.J, Trinh, C.H, Sessions, R.B, Edwards, T.A, Wilson, A.J.
Deposit date:2020-04-30
Release date:2021-01-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of beta-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.
Chem Sci, 12, 2021
7A00
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BU of 7a00 by Molmil
Crystal structure of Shank1 PDZ in complex with L6F mutant of the C-terminal hexapeptide from GKAP
Descriptor: L6F mutant of C-terminal hexapeptide from Guanylate kinase-associated protein, SH3 and multiple ankyrin repeat domains protein 1
Authors:Zsofia, H, Hetherington, K, Fruzsina, H, Edwards, T.A, Wilson, A.J.
Deposit date:2020-08-05
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Query-guided protein-protein interaction inhibitor discovery.
Chem Sci, 12, 2021

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