PDB: 39 resultsInfo pagesStatus searchChemie searchBIRD

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5W3G	Solution Structure of ETS Transcription Factor PU.1 Descriptor: Transcription factor PU.1 Authors: Lau, D.K.W, Okon, M, McIntosh, L.P. Deposit date: 2017-06-07 Release date: 2018-06-13 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Conserved protein dynamics within the ETS transcription factor family To be published
8VDH	Human PU.1 ETS-Domain (165-270) Bound to d(AATAGAAGGAAGTGGG) in Ternary Complex with DB2447 Descriptor: 4,4'-[pyridine-2,6-diylbis(methyleneoxy)]di(benzene-1-carboximidamide), DNA (5'-D(*AP*AP*TP*AP*GP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*TP*AP*T)-3'), ... Authors: Terrell, J.R, Ogbonna, E.N, Poon, G.M.K, Wilson, W.D. Deposit date: 2023-12-15 Release date: 2024-09-18 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Structural Characterization of GC Base Pair Recognition by a Diamidine Small Molecule To Be Published
8VDI	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) in Ternary Complex with DB2447 Descriptor: 4,4'-[pyridine-2,6-diylbis(methyleneoxy)]di(benzene-1-carboximidamide), DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), ... Authors: Terrell, J.R, Ogbonna, E.N, Poon, G.M.K, Wilson, W.D. Deposit date: 2023-12-15 Release date: 2024-09-18 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structural Characterization of GC Base Pair Recognition by a Diamidine Small Molecule To Be Published
1PUE	PU.1 ETS DOMAIN-DNA COMPLEX Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*GP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*CP*CP*TP*TP*TP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR PU.1 (TF PU.1)) Authors: Kodandapani, R, Pio, F, Ni, C.Z, Piccialli, G, Klemsz, M, McKercher, S, Maki, R.A, Ely, K.R. Deposit date: 1996-07-08 Release date: 1997-02-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex. Nature, 380, 1996
6BJ5	Structure of the Clinically used Myxomaviral Serine Protease Inhibitor 1 (SERP-1) Descriptor: 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Mahon, B.P, Lomelino, C.L, McKenna, R. Deposit date: 2017-11-05 Release date: 2018-11-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the Clinically used Myxomaviral Serine Protease Inhibitor 1 (SERP-1) To Be Published
8T9U	Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-06-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8SP1	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-05-01 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8SMJ	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8SMH	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8E4H	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-18 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.39 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3R	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-17 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.45 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3K	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-17 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.28 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E5Y	Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4 Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.32 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EBH	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-31 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.33 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EQG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*DU*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-07 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.39 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKV	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.62 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EM9	Human PU.1 ETS-Domain (165-270) Bound to d(AATAGGAGAAGTAGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*A)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-27 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.341 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8ENG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (forward strand) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*G*(5CM)P*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-29 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.25 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EK3	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-19 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.38 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKZ	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGGAGAAGTAGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.42 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EE9	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-06 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.22 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EMD	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-27 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.55 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EO4	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Di-methylated CpG sites Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-02 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.24 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EJ8	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAAAGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), GLYCEROL, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-16 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.45 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EK8	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAGAAGGG) Descriptor: DNA (5'-D(*AP*TP*AP*AP*AP*AP*GP*GP*AP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*TP*CP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-20 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.63 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023

 

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