2V89
 
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2JWO
 | | A PHD finger motif in the C-terminus of RAG2 modulates recombination activity | | Descriptor: | V(D)J recombination-activating protein 2, ZINC ION | | Authors: | Ivanov, D, Hyberts, S.G, Sun, Z, Wagner, G. | | Deposit date: | 2007-10-17 | | Release date: | 2007-11-06 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
J.Biol.Chem., 280, 2005
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2V86
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2V85
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2V83
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2V88
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2V87
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4WWX
 | | Crystal structure of the core RAG1/2 recombinase | | Descriptor: | V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, ZINC ION | | Authors: | Kim, M.S, Lapkouski, M, Yang, W, Gellert, M. | | Deposit date: | 2014-11-12 | | Release date: | 2015-02-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2001 Å) | | Cite: | Crystal structure of the V(D)J recombinase RAG1-RAG2.
Nature, 518, 2015
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6XNZ
 | | Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex | | Descriptor: | 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ... | | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | | Deposit date: | 2020-07-05 | | Release date: | 2020-08-26 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
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6XNY
 | | Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Paired-Form) | | Descriptor: | 12RSS integration strand (55-mer), 12RSS signal DNA top strand (34-mer), 23RSS integration strand (66-mer), ... | | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | | Deposit date: | 2020-07-05 | | Release date: | 2020-08-26 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
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6XNX
 | | Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Dynamic-Form) | | Descriptor: | 12RSS integration strand DNA (55-MER), 12RSS signal top strand DNA (34-MER), 23RSS integration strand DNA (66-MER), ... | | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | | Deposit date: | 2020-07-05 | | Release date: | 2020-08-26 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
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3JBY
 | | Cryo-electron microscopy structure of RAG Paired Complex (C2 symmetry) | | Descriptor: | '-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', CALCIUM ION, ... | | Authors: | Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H. | | Deposit date: | 2015-10-22 | | Release date: | 2015-12-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
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3JBX
 | | Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry) | | Descriptor: | 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', 5'-D(*GP*CP*GP*AP*TP*GP*GP*TP*TP*AP*AP*CP*CP*A)-3', 5'-D(P*GP*TP*CP*TP*GP*TP*AP*GP*CP*AP*CP*TP*GP*TP*G)-3', ... | | Authors: | Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H. | | Deposit date: | 2015-10-22 | | Release date: | 2015-12-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
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3JBW
 | | Cryo-electron microscopy structure of RAG Paired Complex (with NBD, no symmetry) | | Descriptor: | 12-RSS signal end forward strand, 5'-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', Nicked 12-RSS intermediate reverse strand, ... | | Authors: | Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H. | | Deposit date: | 2015-10-21 | | Release date: | 2015-12-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
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8T4R
 | | RAG2-PHD finger in complex with H3K4tBuNle peptide | | Descriptor: | H3 histone peptide, V(D)J recombination-activating protein 2, ZINC ION | | Authors: | Kean, K.M, Travis, C.R, Waters, M.L. | | Deposit date: | 2023-06-09 | | Release date: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands.
J.Am.Chem.Soc., 146, 2024
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6V0V
 | | Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0) | | Descriptor: | CALCIUM ION, DNA (30-MER), V(D)J recombination-activating protein 1, ... | | Authors: | Chen, X, Yang, W, Gellert, M. | | Deposit date: | 2019-11-19 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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5ZE2
 | | Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C | | Descriptor: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (31-MER), ... | | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | | Deposit date: | 2018-02-25 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
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5ZDZ
 | | Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+ | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DNA (30-MER), ... | | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | | Deposit date: | 2018-02-25 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
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5ZE0
 | | Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ | | Descriptor: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ... | | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | | Deposit date: | 2018-02-25 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
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5ZE1
 | | Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C | | Descriptor: | 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ... | | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | | Deposit date: | 2018-02-25 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
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6OES
 | | Cryo-EM structure of mouse RAG1/2 STC complex (without NBD domain) | | Descriptor: | CALCIUM ION, DNA (34-MER), DNA (35-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
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6OET
 | | Cryo-EM structure of mouse RAG1/2 STC complex | | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (39-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
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6OEO
 | | Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1) | | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.69 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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6OEQ
 | | Cryo-EM structure of mouse RAG1/2 12RSS-PRC/23RSS-NFC complex (DNA1) | | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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6OER
 | | Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2) | | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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