PDB: 14 resultsInfo pagesStatus searchChemie searchBIRD

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8BWF	PTBP1 RRM1 bound to an allosteric inhibitor Descriptor: AMINO GROUP, GLYCEROL, Ligand, ... Authors: Schmeing, S, Vetter, I, t Hart, P, Gasper, R. Deposit date: 2022-12-06 Release date: 2023-10-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding. Chem Sci, 14, 2023
2EVZ	Structure of RNA Binding Domains 3 and 4 of Polypyrimidine Tract Binding Protein Descriptor: Polypyrimidine tract-binding protein 1 Authors: Allain, F.H, Auweter, S.D. Deposit date: 2005-11-01 Release date: 2006-01-17 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Structure of the two most C-terminal RNA recognition motifs of PTB using segmental isotope labeling Embo J., 25, 2006
2N3O	Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA Descriptor: Polypyrimidine tract-binding protein 1, RNA (5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3') Authors: Maris, C, Jayne, S.F, Damberger, F.F, Ravindranathan, S, Allain, F.H.-T. Deposit date: 2015-06-08 Release date: 2016-08-10 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: C-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity. To be Published
8BGF	NMR solution structure of the N-terminal RRM and flanking linker regions of Polypyrimidine tract binding protein 1 using the CYANA CONSENSUS method. Descriptor: Polypyrimidine tract-binding protein 1 Authors: Damberger, F.D, Beusch, I, Allain, F.H.-T. Deposit date: 2022-10-27 Release date: 2023-11-08 Method: SOLUTION NMR Cite: N-terminal domain of Polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition To Be Published
1SJR	NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) Descriptor: Polypyrimidine tract-binding protein 1 Authors: Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J. Deposit date: 2004-03-04 Release date: 2004-09-14 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Structure and RNA Interactions of the N-Terminal RRM Domains of PTB Structure, 12, 2004
1SJQ	NMR Structure of RRM1 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) Descriptor: Polypyrimidine tract-binding protein 1 Authors: Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J. Deposit date: 2004-03-04 Release date: 2004-09-14 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Structure and RNA Interactions of the N-Terminal RRM Domains of PTB Structure, 12, 2004
3ZZY	Crystal structure of a Raver1 PRI3 peptide in complex with polypyrimidine tract binding protein RRM2 Descriptor: POLYPYRIMIDINE TRACT-BINDING PROTEIN 1, RIBONUCLEOPROTEIN PTB-BINDING 1 Authors: Joshi, A, Kotik-Kogan, O, Curry, S. Deposit date: 2011-09-06 Release date: 2011-12-28 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing. Structure, 19, 2011
3ZZZ	Crystal structure of a Raver1 PRI4 peptide in complex with polypyrimidine tract binding protein RRM2 Descriptor: IODIDE ION, POLYPYRIMIDINE TRACT-BINDING PROTEIN 1, RIBONUCLEOPROTEIN PTB-BINDING 1 Authors: Joshi, A, Kotik-Kogan, O, Curry, S. Deposit date: 2011-09-06 Release date: 2011-12-28 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing. Structure, 19, 2011
2ADB	Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 Authors: Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. Deposit date: 2005-07-20 Release date: 2005-10-04 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Structure of PTB bound to RNA: specific binding and implications for splicing regulation Science, 309, 2005
2ADC	Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 Authors: Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. Deposit date: 2005-07-20 Release date: 2005-10-04 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Structure of PTB bound to RNA: specific binding and implications for splicing regulation Science, 309, 2005
2AD9	Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 Authors: Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. Deposit date: 2005-07-20 Release date: 2005-10-04 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Structure of PTB bound to RNA: specific binding and implications for splicing regulation Science, 309, 2005
7AEP	Solution structure of U1-A RRM2 (190-282) Descriptor: U1 small nuclear ribonucleoprotein A Authors: Campagne, S, Allain, F.H. Deposit date: 2020-09-18 Release date: 2021-02-03 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands. Nucleic Acids Res., 49, 2021
6N3H	Crystal structure of Kelch domain of the human NS1 binding protein Descriptor: Influenza virus NS1A-binding protein Authors: Zhang, K, Shang, G, Padavannil, A, Fontoura, B.M.A, Chook, Y.M. Deposit date: 2018-11-15 Release date: 2018-12-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N34	Crystal structure of the BTB domain of Human NS1-BP Descriptor: Influenza virus NS1A-binding protein Authors: Zhang, K, Shang, G, Padavannil, A, Fontoura, B, Chook, Y.M. Deposit date: 2018-11-14 Release date: 2018-12-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. Proc. Natl. Acad. Sci. U.S.A., 115, 2018