PDB: 17 resultsInfo pagesStatus searchChemie searchBIRD

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8G8B	Nucleosome with human nMatn1 sequence in complex with Human Oct4 Descriptor: Histone H2A, Histone H2B, Histone H3, ... Authors: Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. Deposit date: 2023-02-17 Release date: 2023-03-22 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
8G8G	Interaction of H3 tail in LIN28B nucleosome with Oct4 Descriptor: Histone H2A, Histone H2B, Histone H3, ... Authors: Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. Deposit date: 2023-02-17 Release date: 2023-03-22 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
8G87	Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region) Descriptor: POU domain, class 5, transcription factor 1, ... Authors: Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. Deposit date: 2023-02-17 Release date: 2023-03-22 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (8.1 Å) Cite: Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
8G8E	Human Oct4 bound to nucleosome with human LIN28B sequence Descriptor: LIN28B DNA (32-MER), POU domain, class 5, ... Authors: Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. Deposit date: 2023-02-17 Release date: 2023-03-22 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
8G88	Human Oct4 bound to nucleosome with human nMatn1 sequence Descriptor: Histone H2A, Histone H2B, Histone H3, ... Authors: Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. Deposit date: 2023-02-17 Release date: 2023-03-22 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
4RBO	Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution Descriptor: 5'-D(*CP*TP*TP*GP*AP*AP*TP*GP*GP*GP*CP*C)-3', 5'-D(*GP*GP*CP*CP*CP*AP*TP*TP*CP*AP*AP*G)-3', Putative homeobox protein NANOGP8 Authors: Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) Deposit date: 2014-09-12 Release date: 2014-10-01 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proc.Natl.Acad.Sci.USA, 112, 2015
6HT5	Oct4/Sox2:UTF1 structure Descriptor: DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3'), POU domain, ... Authors: Vahokoski, J, Meusch, D, Groves, M, Pogenberg, V, Wilmanns, M. Deposit date: 2018-10-03 Release date: 2019-10-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.451 Å) Cite: Oct4/Sox2:UTF1 structure To Be Published
6YOV	OCT4-SOX2-bound nucleosome - SHL+6 Descriptor: DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... Authors: Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. Deposit date: 2020-04-15 Release date: 2020-05-06 Last modified: 2020-07-08 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
8OTS	OCT4 and MYC-MAX co-bound to a nucleosome Descriptor: DNA (127-MER), Green fluorescent protein,POU domain, class 5, ... Authors: Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N. Deposit date: 2023-04-21 Release date: 2023-05-24 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
6T90	OCT4-SOX2-bound nucleosome - SHL-6 Descriptor: DNA (146-MER), Green fluorescent protein,POU domain, class 5, ... Authors: Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. Deposit date: 2019-10-25 Release date: 2020-05-06 Last modified: 2020-07-08 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
8SPS	High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b Descriptor: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2023-05-03 Release date: 2023-06-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
8SPU	Structure of ESRRB nucleosome bound OCT4 at site c Descriptor: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2023-05-03 Release date: 2023-06-28 Last modified: 2024-02-07 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
8BX1	Oct4/Sox2 protein:DNA complex Descriptor: HOXB1_f, HOXB1_r, POU domain, ... Authors: Chojnowski, G, Wilmanns, M, Round, E. Deposit date: 2022-12-07 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of Oct4-Soc2-HoxB1 complex To Be Published
8BX2	Oct4/Sox2 protein:DNA complex Descriptor: POU domain, class 5, transcription factor 1, ... Authors: Chojnowski, G, Wilmanns, M, Round, E. Deposit date: 2022-12-07 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (3.14 Å) Cite: Crystal structure of Oct4-Soc2-UTF1 complex To Be Published
7U0I	Structure of LIN28b nucleosome bound 2 OCT4 Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Tengfei, L, Guan, R, Bai, Y. Deposit date: 2022-02-18 Release date: 2023-06-28 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
7U0G	structure of LIN28b nucleosome bound 3 OCT4 Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... Authors: Lian, T, Guan, R, Bai, Y. Deposit date: 2022-02-18 Release date: 2023-06-28 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
8G86	Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome) Descriptor: Histone H2A, Histone H2B, Histone H3, ... Authors: Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. Deposit date: 2023-02-17 Release date: 2023-03-22 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023