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2CXC
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Crystal structure of archaeal transcription termination factor NusA
Descriptor: NusA
Authors:Shibata, R, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-28
Release date:2005-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA
Biochem.Biophys.Res.Commun., 355, 2007
2CY1
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BU of 2cy1 by Molmil
Crystal structure of APE1850
Descriptor: NusA protein homolog
Authors:Shibata, R, Bessho, Y, Umehara, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-04
Release date:2006-01-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions
Acta Crystallogr.,Sect.F, 63, 2007
1WH9
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BU of 1wh9 by Molmil
Solution structure of the KH domain of human ribosomal protein S3
Descriptor: 40S ribosomal protein S3
Authors:Nameki, N, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-28
Release date:2004-11-28
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the KH domain of human ribosomal protein S3
To be Published
5ZEU
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BU of 5zeu by Molmil
M. smegmatis P/P state 30S ribosomal subunit
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S.
Deposit date:2018-02-28
Release date:2018-09-26
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Sci Rep, 8, 2018
1VVJ
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BU of 1vvj by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Maehigashi, T, Dunkle, J.A, Dunham, C.M.
Deposit date:2013-05-24
Release date:2014-08-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.440001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
5CZP
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BU of 5czp by Molmil
70S termination complex containing E. coli RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2015-07-31
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.29995918 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
3T1Y
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
Deposit date:2011-07-22
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
3T1H
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BU of 3t1h by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
Descriptor: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
Deposit date:2011-07-21
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
4GKJ
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BU of 4gkj by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin.
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F.
Deposit date:2012-08-11
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Expanded use of sense codons is regulated by modified cytidines in tRNA.
Proc.Natl.Acad.Sci.USA, 110, 2013
2HHH
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BU of 2hhh by Molmil
Crystal structure of kasugamycin bound to the 30S ribosomal subunit
Descriptor: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Schluenzen, F.
Deposit date:2006-06-28
Release date:2006-09-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006
2F4V
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BU of 2f4v by Molmil
30S ribosome + designer antibiotic
Descriptor: (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ...
Authors:Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S.
Deposit date:2005-11-24
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
1EGA
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BU of 1ega by Molmil
CRYSTAL STRUCTURE OF A WIDELY CONSERVED GTPASE ERA
Descriptor: PROTEIN (GTP-BINDING PROTEIN ERA), SULFATE ION
Authors:Chen, X, Ji, X.
Deposit date:1998-12-01
Release date:1999-07-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif.
Proc.Natl.Acad.Sci.USA, 96, 1999
1FJG
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BU of 1fjg by Molmil
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V.
Deposit date:2000-08-08
Release date:2000-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
4GKK
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUA-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F.
Deposit date:2012-08-11
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Expanded use of sense codons is regulated by modified cytidines in tRNA.
Proc.Natl.Acad.Sci.USA, 110, 2013
3OTO
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BU of 3oto by Molmil
Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8)
Descriptor: 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G.
Deposit date:2010-09-13
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
2XR1
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BU of 2xr1 by Molmil
DIMERIC ARCHAEAL CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR WITH N-TERMINAL KH DOMAINS (KH-CPSF) FROM METHANOSARCINA MAZEI
Descriptor: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100 KD SUBUNIT, ZINC ION
Authors:Mir-Montazeri, B, Ammelburg, M, Forouzan, D, Lupas, A.N, Hartmann, M.D.
Deposit date:2010-09-08
Release date:2010-10-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal Structure of a Dimeric Archaeal Cleavage and Polyadenylation Specificity Factor.
J.Struct.Biol., 173, 2011
3R9X
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BU of 3r9x by Molmil
Crystal structure of Era in complex with MgGDPNP, nucleotides 1506-1542 of 16S ribosomal RNA, and KsgA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, GTPase Era, ...
Authors:Tu, C, Ji, X.
Deposit date:2011-03-26
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
3R9W
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BU of 3r9w by Molmil
Crystal structure of Era in complex with MgGDPNP and nucleotides 1506-1542 of 16S ribosomal RNA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, CALCIUM ION, ...
Authors:Tu, C, Ji, X.
Deposit date:2011-03-26
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
2ZM6
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BU of 2zm6 by Molmil
Crystal structure of the Thermus thermophilus 30S ribosomal subunit
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Kaminishi, T, Wang, H, Kawazoe, M, Ishii, R, Schluenzen, F, Hanawa-Suetsugu, K, Wilson, D.N, Nomura, M, Takemoto, C, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-04-11
Release date:2009-04-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the Thermus thermophilus 30S ribosomal subunit
To be Published
2YKR
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BU of 2ykr by Molmil
30S ribosomal subunit with RsgA bound in the presence of GMPPNP
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Guo, Q, Yuan, Y, Xu, Y, Feng, B, Liu, L, Chen, K, Lei, J, Gao, N.
Deposit date:2011-05-30
Release date:2011-08-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Proc.Natl.Acad.Sci.USA, 108, 2011
8JDM
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BU of 8jdm by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDL
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BU of 8jdl by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDJ
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BU of 8jdj by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDK
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BU of 8jdk by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
2BA0
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BU of 2ba0 by Molmil
Archaeal exosome core
Descriptor: Archaeal exosome RNA binding protein RRP4, Archaeal exosome RNA binding protein RRP41, Archaeal exosome RNA binding protein RRP42
Authors:Buttner, K, Wenig, K, Hopfner, K.P.
Deposit date:2005-10-13
Release date:2005-11-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural framework for the mechanism of archaeal exosomes in RNA processing.
Mol.Cell, 20, 2005

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