1GWB
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STRUCTURE OF GLYCOPROTEIN 1B
Descriptor:PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Authors:Emsley, J., Uff, S., Clemetson, K.J.M., Clemetson, J.M., Harrison, T.
Deposit date:2002-03-14
Release date:2003-02-06
Modification date:2012-01-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals an Unmasking Mechanism of Receptor Activation
J.Biol.Chem., 277, 2002
1M0Z
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CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR BINDING DOMAIN OF GLYCOPROTEIN IB ALPHA
Descriptor:Platelet glycoprotein Ib alpha chain
Authors:Huizinga, E.G., Tsuji, S., Romijn, R.A.P., Schiphorst, M.E., de Groot, P.G., Sixma, J.J., Gros, P.
Deposit date:2002-06-16
Release date:2002-08-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
1P8V
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CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A
Descriptor:Platelet glycoprotein Ib alpha chain, Prothrombin (E.C.3.4.21.5)
Authors:Dumas, J.J., Kumar, R., Seehra, J., Somers, W.S., Mosyak, L.
Deposit date:2003-05-07
Release date:2003-07-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation
Science, 301, 2003
1P9A
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF HUMAN PLATELET RECEPTOR GLYCOPROTEIN IB-ALPHA AT 1.7 ANGSTROM RESOLUTION
Descriptor:Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin]
Authors:Varughese, K.I., Celikel, R., Ruggeri, Z.M.
Deposit date:2003-05-09
Release date:2003-07-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
1QYY
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF HUMAN PLATELET RECEPTOR GLYCOPROTEIN IB-ALPHA AT 2.8 ANGSTROM RESOLUTION
Descriptor:Platelet glycoprotein Ib alpha chain
Authors:Varughese, K.I., Ruggeri, Z.M., Celikel, R.
Deposit date:2003-09-12
Release date:2004-03-02
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain.
Acta Crystallogr.,Sect.D, 60, 2004
1W8A
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THIRD LRR DOMAIN OF DROSOPHILA SLIT
Descriptor:SLIT PROTEIN
Authors:Howitt, J.A., Clout, N.J., Hohenester, E.
Deposit date:2004-09-17
Release date:2004-10-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Site for Robo Receptors Revealed by Dissection of the Leucine-Rich Repeat Region of Slit.
Embo J., 23, 2004
1XCD
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DIMERIC BOVINE TISSUE-EXTRACTED DECORIN, CRYSTAL FORM 1
Descriptor:Decorin
Authors:Scott, P.G., McEwan, P.A., Dodd, C.M., Bergmann, E.M., Bishop, P.N., Bella, J.
Deposit date:2004-09-01
Release date:2004-11-02
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
1XEC
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DIMERIC BOVINE TISSUE-EXTRACTED DECORIN, CRYSTAL FORM 2
Descriptor:Decorin
Authors:Scott, P.G., McEwan, P.A., Dodd, C.M., Bergmann, E.M., Bishop, P.N., Bella, J.
Deposit date:2004-09-09
Release date:2004-11-02
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.USA, 101, 2004
1XKU
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CRYSTAL STRUCTURE OF THE DIMERIC PROTEIN CORE OF DECORIN, THE ARCHETYPAL SMALL LEUCINE-RICH REPEAT PROTEOGLYCAN
Descriptor:Decorin
Authors:Scott, P.G., McEwan, P.A., Dodd, C.M., Bergmann, E.M., Bishop, P.N., Bella, J.
Deposit date:2004-09-29
Release date:2004-11-02
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
2FT3
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CRYSTAL STRUCTURE OF THE BIGLYCAN DIMER CORE PROTEIN
Descriptor:Biglycan
Authors:Scott, P.G., Dodd, C.M., Bergmann, E.M.
Deposit date:2006-01-23
Release date:2006-03-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of the Biglycan Dimer and Evidence That Dimerization Is Essential for Folding and Stability of Class I Small Leucine-rich Repeat Proteoglycans.
J.Biol.Chem., 281, 2006
2V70
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THIRD LRR DOMAIN OF HUMAN SLIT2
Descriptor:SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C., Cusack, S., Mccarthy, A.A.
Deposit date:2007-07-24
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Production of Slit2 Lrr Domains in Mammalian Cells for Structural Studies and the Structure of Human Slit2 Domain 3.
Acta Crystallogr.,Sect.D, 63, 2007
2V9S
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SECOND LRR DOMAIN OF HUMAN SLIT2
Descriptor:SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C., Cusack, S., McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Modification date:2014-11-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2WFH
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THE HUMAN SLIT 2 DIMERIZATION DOMAIN D4
Descriptor:SLIT HOMOLOG 2 PROTEIN C-PRODUCT
Authors:Seiradake, E., Von Philipsborn, A.C., Henry, M., Fritz, M., Lortat-Jacob, H., Jamin, M., Hemrika, W., Bastmeyer, M., Cusack, S., Mccarthy, A.A.
Deposit date:2009-04-06
Release date:2009-04-21
Modification date:2011-09-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Functional Relevance of the Slit2 Homodimerization Domain.
Embo Rep., 10, 2009
3P72
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STRUCTURE OF PLATELET GLYCOPROTEIN 1B ALPHA WITH A BOUND PEPTIDE INHIBITOR
Descriptor:Platelet glycoprotein Ib alpha chain/OS1 peptide complex
Authors:McEwan, P.A., Andrews, R.K., Emsley, J.
Deposit date:2010-10-12
Release date:2010-11-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism.
Blood, 114, 2009
4BSR
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STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-1 (FU1FU2) IN P22121 CRYSTAL FORM
Descriptor:LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1
Authors:Peng, W.C., de Lau, W., Forneris, F., Granneman, J.C.M., Huch, M., Clevers, H., Gros, P.
Deposit date:2013-06-11
Release date:2013-06-19
Modification date:2013-07-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSS
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STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-1 (FU1FU2) IN P21 CRYSTAL FORM
Descriptor:LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1
Authors:Peng, W.C., de Lau, W., Forneris, F., Granneman, J.C.M., Huch, M., Clevers, H., Gros, P.
Deposit date:2013-06-11
Release date:2013-06-19
Modification date:2013-07-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BST
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STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-1 (FU1FU2) IN P6122 CRYSTAL FORM
Descriptor:LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1
Authors:Peng, W.C., de Lau, W., Forneris, F., Granneman, J.C.M., Huch, M., Clevers, H., Gros, P.
Deposit date:2013-06-11
Release date:2013-06-19
Modification date:2013-07-24
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSU
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STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-1 (FU1FU2) IN C2 CRYSTAL FORM
Descriptor:LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1
Authors:Peng, W.C., de Lau, W., Forneris, F., Granneman, J.C.M., Huch, M., Clevers, H., Gros, P.
Deposit date:2013-06-11
Release date:2013-06-26
Modification date:2013-07-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4CNC
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CRYSTAL STRUCTURE OF HUMAN 5T4 (WNT-ACTIVATED INHIBITORY FACTOR 1, TROPHOBLAST GLYCOPROTEIN)
Descriptor:TROPHOBLAST GLYCOPROTEIN
Authors:Zhao, Y., Malinauskas, T., Harlos, K., Jones, E.Y.
Deposit date:2014-01-21
Release date:2014-02-26
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Structure, 22, 2014
4CNM
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CRYSTAL STRUCTURE OF HUMAN 5T4 (WNT-ACTIVATED INHIBITORY FACTOR 1, TROPHOBLAST GLYCOPROTEIN)
Descriptor:TROPHOBLAST GLYCOPROTEIN
Authors:Zhao, Y., Malinauskas, T., Harlos, K., Jones, E.Y.
Deposit date:2014-01-23
Release date:2014-02-26
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Structure, 22, 2014
4KNG
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CRYSTAL STRUCTURE OF HUMAN LGR5-RSPO1-RNF43
Descriptor:Leucine-rich repeat-containing G-protein coupled receptor 5, R-spondin-1, E3 ubiquitin-protein ligase RNF43 (E.C.6.3.2.-)
Authors:Chen, P.H., He, X.
Deposit date:2013-05-09
Release date:2013-06-19
Modification date:2013-07-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis of R-spondin recognition by LGR5 and RNF43.
Genes Dev., 27, 2013
4KT1
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COMPLEX OF R-SPONDIN 1 WITH LGR4 EXTRACELLULAR DOMAIN
Descriptor:Leucine-rich repeat-containing G-protein coupled receptor 4, R-spondin-1
Authors:Wang, X.Q., Wang, D.L.
Deposit date:2013-05-19
Release date:2013-06-19
Modification date:2013-08-14
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for R-spondin recognition by LGR4/5/6 receptors
Genes Dev., 27, 2013
4QXE
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CRYSTAL STRUCTURE OF LGR4 FUSED WITH HAGFISH VLR
Descriptor:Leucine-rich repeat-containing G-protein coupled receptor 4, Variable lymphocyte receptor B
Authors:Xu, J.G., Huang, C., Zhu, Y.
Deposit date:2014-07-20
Release date:2014-10-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of LGR4 fused with hagfish VLR
TO BE PUBLISHED
4QXF
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CRYSTAL STRUCTURE OF HUMAN LGR4 AND RSPO1
Descriptor:Leucine-rich repeat-containing G-protein coupled receptor 4, Variable lymphocyte receptor B, R-spondin-1
Authors:Xu, J.G., Huang, C., Zhou, Y., Zhu, Y.
Deposit date:2014-07-20
Release date:2014-10-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:crystal structure of human LGR4 and Rspo1
TO BE PUBLISHED
4UFR
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STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-2 (FU1FU2)
Descriptor:LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-2
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2015-03-18
Release date:2015-07-08
Modification date:2015-09-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of R-Spondin 2 in Complex with the Ectodomains of its Receptors Lgr5 and Znrf3.
J.Struct.Biol., 191, 2015
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