1KU9
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X-RAY STRUCTURE OF A METHANOCOCCUS JANNASCHII DNA-BINDING PROTEIN: IMPLICATIONS FOR ANTIBIOTIC RESISTANCE IN STAPHYLOCOCCUS AUREUS
Descriptor:hypothetical protein MJ223
Authors:Ray, S.S., Bonanno, J.B., Chen, H., de Lencastre, H., Wu, S., Tomasz, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-01-21
Release date:2002-12-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus
Proteins, 50, 2002
1R1T
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CRYSTAL STRUCTURE OF THE CYANOBACTERIAL METALLOTHIONEIN REPRESSOR SMTB IN THE APO-FORM
Descriptor:Transcriptional repressor smtB
Authors:Eicken, C., Pennella, M.A., Chen, X., Koshlap, K.M., VanZile, M.L., Sacchettini, J.C., Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R1U
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CRYSTAL STRUCTURE OF THE METAL-SENSING TRANSCRIPTIONAL REPRESSOR CZRA FROM STAPHYLOCOCCUS AUREUS IN THE APO-FORM
Descriptor:repressor protein
Authors:Eicken, C., Pennella, M.A., Chen, X., Koshlap, K.M., VanZile, M.L., Sacchettini, J.C., Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R1V
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CRYSTAL STRUCTURE OF THE METAL-SENSING TRANSCRIPTIONAL REPRESSOR CZRA FROM STAPHYLOCOCCUS AUREUS IN THE ZN2-FORM
Descriptor:repressor protein
Authors:Eicken, C., Pennella, M.A., Chen, X., Koshlap, K.M., VanZile, M.L., Sacchettini, J.C., Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R22
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CRYSTAL STRUCTURE OF THE CYANOBACTERIAL METALLOTHIONEIN REPRESSOR SMTB (C14S/C61S/C121S MUTANT) IN THE ZN2ALPHA5-FORM
Descriptor:Transcriptional repressor smtB
Authors:Eicken, C., Pennella, M.A., Chen, X., Koshlap, K.M., VanZile, M.L., Sacchettini, J.C., Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R23
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CRYSTAL STRUCTURE OF THE CYANOBACTERIAL METALLOTHIONEIN REPRESSOR SMTB IN THE ZN1-FORM (ONE ZN(II) PER DIMER)
Descriptor:Transcriptional repressor smtB
Authors:Eicken, C., Pennella, M.A., Chen, X., Koshlap, K.M., VanZile, M.L., Sacchettini, J.C., Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1SMT
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SMTB REPRESSOR FROM SYNECHOCOCCUS PCC7942
Descriptor:TRANSCRIPTIONAL REPRESSOR SMTB
Authors:Cook, W.J., Hall, L.M.
Deposit date:1997-09-16
Release date:1997-12-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the cyanobacterial metallothionein repressor SmtB: a model for metalloregulatory proteins.
J.Mol.Biol., 275, 1998
1U2W
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CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS PI258 CADC
Descriptor:Cadmium efflux system accessory protein
Authors:Ye, J., Kandegedara, A., Martin, P., Rosen, B.P.
Deposit date:2004-07-20
Release date:2005-07-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Staphylococcus aureus pI258 CadC Cd(II)/Pb(II)/Zn(II)-responsive repressor
J.Bacteriol., 187, 2005
1ULY
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CRYSTAL STRUCTURE ANALYSIS OF THE ARSR HOMOLOGUE DNA-BINDING PROTEIN FROM P. HORIKOSHII OT3
Descriptor:hypothetical protein PH1932
Authors:Itou, H., Yao, M., Watanabe, N., Tanaka, I.
Deposit date:2003-09-17
Release date:2004-10-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the PH1932 protein, a unique archaeal ArsR type winged-HTH transcription factor from Pyrococcus horikoshii OT3
Proteins, 70, 2008
2CWE
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CRYSTAL STRUCTURE OF HYPOTHETICAL TRANSCRIPTIONAL REGULATOR PROTEIN, PH1932 FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:hypothetical transcription regulator protein, PH1932
Authors:Arai, R., Kishishita, S., Kukimoto-Niino, M., Wang, H., Sugawara, M., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-20
Release date:2005-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of hypothetical transcriptional regulator protein, PH1932 from Pyrococcus horikoshii OT3
To be Published
2JSC
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NMR STRUCTURE OF THE CADMIUM METAL-SENSOR CMTR FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Transcriptional regulator Rv1994c/MT2050
Authors:Banci, L., Bertini, I., Cantini, F., Ciofi-Baffoni, S., Cavet, J.S., Dennison, C., Graham, A.I., Harvie, D.R., Robinson, N.J., Structural Proteomics in Europe (SPINE)
Deposit date:2007-07-02
Release date:2007-07-31
Modification date:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structural Analysis of Cadmium Sensing by Winged Helix Repressor CmtR.
J.Biol.Chem., 282, 2007
2KJB
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SOLUTION STRUCTURE OF CZRA IN THE DNA BOUND STATE
Descriptor:CzrA protein
Authors:Arunkumar, A.I., Campanello, G.C., Giedroc, D.P.
Deposit date:2009-05-27
Release date:2009-11-10
Method:SOLUTION NMR
Cite:Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state
Proc.Natl.Acad.Sci.USA, 106, 2009
2KJC
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SOLUTION STRUCTURE OF CZRA IN THE ZN(II) STATE
Descriptor:CzrA protein
Authors:Arunkumar, A.I., Campanello, G.C., Giedroc, D.P.
Deposit date:2009-05-27
Release date:2009-11-10
Method:SOLUTION NMR
Cite:Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state
Proc.Natl.Acad.Sci.USA, 106, 2009
2LKP
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SOLUTION STRUCTURE OF APO-NMTR
Descriptor:Transcriptional regulator, ArsR family
Authors:Lee, C., Giedroc, D.
Deposit date:2011-10-18
Release date:2012-04-18
Method:SOLUTION NMR
Cite:Solution Structure of Mycobacterium tuberculosis NmtR in the Apo State: Insights into Ni(II)-Mediated Allostery.
Biochemistry, 51, 2012
2M30
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SOLUTION NMR REFINEMENT OF A METAL ION BOUND PROTEIN USING QUANTUM MECHANICAL/MOLECULAR MECHANICAL AND MOLECULAR DYNAMICS METHODS
Descriptor:Repressor protein
Authors:Chakravorty, D.K., Wang, B.I., Lee, C.I., Guerra, A.J., Giedroc, D.P., Merz Jr., K.M., Arunkumar, A.I., Pennella, M., Kong, X.
Deposit date:2013-01-04
Release date:2013-05-08
Modification date:2013-07-24
Method:SOLUTION NMR
Cite:Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods.
J.Biomol.Nmr, 56, 2013
2P4W
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CRYSTAL STRUCTURE OF HEAT SHOCK REGULATOR FROM PYROCOCCUS FURIOSUS
Descriptor:Transcriptional regulatory protein arsR family
Authors:Liu, W., Vierke, G., Panjikar, S., Thomm, M., Ladenstein, R.
Deposit date:2007-03-13
Release date:2007-03-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Archaeal Heat Shock Regulator from Pyrococcus furiosus: A Molecular Chimera Representing Eukaryal and Bacterial Features.
J.Mol.Biol., 369, 2007
2ZKZ
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CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL REPRESSOR PAGR OF BACILLUS ANTHRACIS
Descriptor:Transcriptional repressor pagR
Authors:Zhao, H., Volkov, A., Veldore, V.H., Varughese, K.I.
Deposit date:2008-04-01
Release date:2009-04-07
Modification date:2011-11-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the transcriptional repressor PagR of Bacillus anthracis
Microbiology, 156, 2010
3CUO
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CRYSTAL STRUCTURE OF THE PREDICTED DNA-BINDING TRANSCRIPTIONAL REGULATOR FROM E. COLI
Descriptor:Uncharacterized HTH-type transcriptional regulator ygaV
Authors:Zhang, R., Evdokimova, E., Kagan, O., Savchenko, A., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-04-16
Release date:2008-06-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the predicted DNA-binding transcriptional regulator from E. coli.
To be Published
3F6V
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CRYSTAL STRUCTURE OF POSSIBLE TRANSCRIPTIONAL REGULATOR FOR ARSENICAL RESISTANCE
Descriptor:Possible transcriptional regulator, ArsR family protein
Authors:Chang, C., Xu, X., Zheng, H., Savchenko, A., Edwards, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-11-06
Release date:2008-11-25
Modification date:2014-09-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of Possible transcriptional regulator for arsenical resistance from Rhodococcus sp.
To be Published
3F72
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CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS PI258 CADC METAL BINDING SITE 2 MUTANT
Descriptor:CadC Dimerization Double Mutant
Authors:Kandegedara, A., Thiyagarajan, S., Kondapalli, K.C., Stemmler, T.L., Rosen, B.P.
Deposit date:2008-11-07
Release date:2009-04-07
Modification date:2009-06-30
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Role of bound Zn(II) in the CadC Cd(II)/Pb(II)/Zn(II)-responsive repressor.
J.Biol.Chem., 284, 2009
4GGG
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CRYSTAL STRUCTURE OF V66A/L68V CZRA IN THE ZN(II)BOUND STATE.
Descriptor:Repressor protein
Authors:Campanello, G.C., Ma, Z., Grossoehme, N.E., Chakrovorty, D.K., Guerra, A.J., Ye, Y., Dann III, C.E., Merz, Jr., K.M., Giedroc, D.P.
Deposit date:2012-08-06
Release date:2013-02-06
Modification date:2013-05-22
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Allosteric inhibition of a zinc-sensing transcriptional repressor: insights into the arsenic repressor (ArsR) family.
J.Mol.Biol., 425, 2013
4K2E
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HLYU FROM VIBRIO CHOLERAE N16961
Descriptor:Transcriptional activator HlyU
Authors:Mukherjee, D., Datta, A.B., Chakrabarti, P.
Deposit date:2013-04-09
Release date:2014-04-30
Modification date:2014-12-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications.
Biochim.Biophys.Acta, 1844, 2014
4OMY
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CRYSTAL STRUCTURE OF SEMET NOLR FROM SINORHIZOBIUM FREDII IN COMPLEX WITH OLIGO AT DNA
Descriptor:NolR
Authors:Lee, S.G., Krishnan, H.B., Jez, J.M.
Deposit date:2014-01-28
Release date:2014-04-16
Modification date:2014-06-04
Method:X-RAY DIFFRACTION (3.062 Å)
Cite:Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OMZ
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CRYSTAL STRUCTURE OF NOLR FROM SINORHIZOBIUM FREDII
Descriptor:NolR
Authors:Lee, S.G., Krishnan, H.B., Jez, J.M.
Deposit date:2014-01-28
Release date:2014-04-16
Modification date:2014-06-04
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR.
Proc.Natl.Acad.Sci.USA, 111, 2014
4ON0
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CRYSTAL STRUCTURE OF NOLR FROM SINORHIZOBIUM FREDII IN COMPLEX WITH OLIGO AA DNA
Descriptor:NolR
Authors:Lee, S.G., Krishnan, H.B., Jez, J.M.
Deposit date:2014-01-28
Release date:2014-04-16
Modification date:2014-06-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR.
Proc.Natl.Acad.Sci.USA, 111, 2014
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