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3WGW
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BU of 3wgw by Molmil
Structure of PCNA bound to a small molecule inhibitor
Descriptor: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION
Authors:Hashimoto, H.
Deposit date:2013-08-12
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
J.Biol.Chem., 289, 2014
8COB
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BU of 8cob by Molmil
Crystal structure of human PCNA in complex with ERCC6L2 PIP box peptide
Descriptor: DNA excision repair protein ERCC-6-like 2, Proliferating cell nuclear antigen
Authors:Ariza, A.
Deposit date:2023-02-27
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:ERCC6L2 mitigates replication stress and promotes centromere stability.
Cell Rep, 42, 2023
3L0X
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BU of 3l0x by Molmil
Structure of split yeast PCNA
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
6WAC
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BU of 6wac by Molmil
FF248-249AA PCNA mutant defective in BIR
Descriptor: Proliferating cell nuclear antigen
Authors:Ripley, B.M, Washington, M.T.
Deposit date:2020-03-25
Release date:2020-09-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
4CS5
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BU of 4cs5 by Molmil
Crystal Structure of PCNA from Litopenaeus vannamei
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R.
Deposit date:2014-03-04
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box.
Plos One, 9, 2014
1AXC
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BU of 1axc by Molmil
HUMAN PCNA
Descriptor: P21/WAF1, PCNA
Authors:Gulbis, J.M, Kuriyan, J.
Deposit date:1997-10-14
Release date:1998-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell(Cambridge,Mass.), 87, 1996
4RJF
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BU of 4rjf by Molmil
Crystal structure of the human sliding clamp at 2.0 angstrom resolution
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Kroker, A.J, Bruning, J.B.
Deposit date:2014-10-09
Release date:2015-08-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.0072 Å)
Cite:p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
Biochemistry, 54, 2015
6O09
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BU of 6o09 by Molmil
Structure of AtPCNA in complex with the PIP motif of ATXR6
Descriptor: Proliferating cellular nuclear antigen 1, Uncharacterized protein
Authors:Couture, J.F, Davarinejad, H.
Deposit date:2019-02-15
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle.
J. Mol. Biol., 431, 2019
8B8T
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BU of 8b8t by Molmil
Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP
Descriptor: DNA ligase 1, Proliferating cell nuclear antigen
Authors:Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
Deposit date:2022-10-05
Release date:2023-01-11
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
4D2G
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BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
7WP3
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BU of 7wp3 by Molmil
Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
Descriptor: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Proliferating cell nuclear antigen
Authors:Ahmad, M.I, Yadav, S.P, Singh, P.K, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2022-01-22
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.954 Å)
Cite:Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
To Be Published
1GE8
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BU of 1ge8 by Molmil
PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) HOMOLOG FROM PYROCOCCUS FURIOSUS
Descriptor: PROLIFERATION CELL NUCLEAR ANTIGEN
Authors:Matsumiya, S, Ishino, Y, Morikawa, K.
Deposit date:2000-10-18
Release date:2001-01-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus.
Protein Sci., 10, 2001
5T9D
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BU of 5t9d by Molmil
Structure of PCNA acetylated on K20
Descriptor: Proliferating cell nuclear antigen
Authors:Couture, J.F, Tremblay, V, Brunzelle, J.S.
Deposit date:2016-09-09
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure of PCNA acetylated on K20
To Be Published
5MLO
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BU of 5mlo by Molmil
Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide
Descriptor: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide
Authors:Ariza, A.
Deposit date:2016-12-07
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
7EP8
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BU of 7ep8 by Molmil
Crystal structure of PCNA from Neurospora crassa
Descriptor: Proliferating cell nuclear antigen
Authors:Sundaram, R, Vasudevan, D.
Deposit date:2021-04-26
Release date:2021-06-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.
J.Biol.Chem., 297, 2021
6W9W
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BU of 6w9w by Molmil
R80A PCNA mutant defective in BIR
Descriptor: Proliferating cell nuclear antigen
Authors:Ripley, B.M, Washington, M.T.
Deposit date:2020-03-23
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
5MOM
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BU of 5mom by Molmil
Crystal Structure of PCNA encoding the hypomorphic mutation S228I
Descriptor: Proliferating cell nuclear antigen
Authors:Biasutto, A.J, Mancini, E.J, Green, C.M, Wilson, R.H.C.
Deposit date:2016-12-14
Release date:2017-01-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions.
DNA Repair (Amst.), 50, 2017
5MLW
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BU of 5mlw by Molmil
Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide
Descriptor: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION
Authors:Ariza, A.
Deposit date:2016-12-07
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
5MAV
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BU of 5mav by Molmil
Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide.
Descriptor: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen
Authors:Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
Deposit date:2016-11-06
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.575 Å)
Cite:A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Nucleic Acids Res., 45, 2017
6FCM
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BU of 6fcm by Molmil
Crystal structure of human PCNA
Descriptor: Proliferating cell nuclear antigen
Authors:Housset, D, Frachet, P.
Deposit date:2017-12-20
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
6FCN
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BU of 6fcn by Molmil
Crystal structure of human PCNA soaked with p47phox(106-127) peptide
Descriptor: Proliferating cell nuclear antigen
Authors:Housset, D, Frachet, P.
Deposit date:2017-12-20
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
2NTI
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BU of 2nti by Molmil
Crystal structure of PCNA123 heterotrimer.
Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ...
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-11-07
Release date:2007-12-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
3F1W
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BU of 3f1w by Molmil
Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Ramaswamy, S, Washington, M.T.
Deposit date:2008-10-28
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis.
Biochemistry, 47, 2008
2OD8
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BU of 2od8 by Molmil
Structure of a peptide derived from Cdc9 bound to PCNA
Descriptor: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen
Authors:Chapados, B.R, Tainer, J.A.
Deposit date:2006-12-21
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
Nucleic Acids Res., 35, 2007
7EFA
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BU of 7efa by Molmil
Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA
Descriptor: Adenine DNA glycosylase, Proliferating cell nuclear antigen
Authors:Nakamura, T, Nakabeppu, Y, Yamagata, Y.
Deposit date:2021-03-21
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021

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