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8OM1
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Mitochondrial complex I from Mus musculus in the active state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-03-31
Release date:2023-08-09
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
8OLT
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Mitochondrial complex I from Mus musculus in the active state bound with piericidin A
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-03-30
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
8ESZ
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Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
Descriptor: (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Padavannil, A, Letts, J.A.
Deposit date:2022-10-15
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Elife, 12, 2023
8ESW
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Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Padavannil, A, Letts, J.A.
Deposit date:2022-10-15
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Elife, 12, 2023
8E9I
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Mycobacterial respiratory complex I, semi-inserted quinone
Descriptor: (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Liang, Y, Rubinstein, J.L.
Deposit date:2022-08-26
Release date:2022-10-12
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of mycobacterial respiratory complex I.
Proc.Natl.Acad.Sci.USA, 120, 2023
8E9H
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BU of 8e9h by Molmil
Mycobacterial respiratory complex I, fully-inserted quinone
Descriptor: (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Liang, Y, Rubinstein, J.L.
Deposit date:2022-08-26
Release date:2022-10-12
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of mycobacterial respiratory complex I.
Proc.Natl.Acad.Sci.USA, 120, 2023
8E9G
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BU of 8e9g by Molmil
Mycobacterial respiratory complex I with both quinone positions modelled
Descriptor: (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Liang, Y, Rubinstein, J.L.
Deposit date:2022-08-26
Release date:2022-10-12
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of mycobacterial respiratory complex I.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CA5
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Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3).
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-01-24
Release date:2023-12-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.
Embo J., 43, 2024
8CA3
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Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2).
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2023-01-24
Release date:2023-12-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.
Embo J., 43, 2024
8C2S
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BU of 8c2s by Molmil
Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1).
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J.
Deposit date:2022-12-22
Release date:2023-12-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.
Embo J., 43, 2024
8BQ6
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BU of 8bq6 by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2 composition)
Descriptor: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-11-18
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BQ5
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BU of 8bq5 by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1 composition)
Descriptor: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-11-18
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BPX
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BU of 8bpx by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete composition)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-11-18
Release date:2023-01-25
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BEF
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BU of 8bef by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-10-21
Release date:2023-01-11
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (2.13 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BA0
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BU of 8ba0 by Molmil
Drosophila melanogaster complex I in the Twisted state (Dm2)
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ...
Authors:Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J.
Deposit date:2022-10-10
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
8B9Z
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BU of 8b9z by Molmil
Drosophila melanogaster complex I in the Active state (Dm1)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J.
Deposit date:2022-10-10
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
7ZMH
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BU of 7zmh by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZMG
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BU of 7zmg by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZME
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BU of 7zme by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZMB
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BU of 7zmb by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZM8
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BU of 7zm8 by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZM7
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BU of 7zm7 by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZKP
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BU of 7zkp by Molmil
Late assembly intermediate of the proximal proton pumping module of complex I with assembly factors NDUFAF1 and CIA84
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, ...
Authors:Schiller, J, Laube, E, Vonck, J, Zickermann, V.
Deposit date:2022-04-13
Release date:2022-11-23
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling.
Sci Adv, 8, 2022
7ZEB
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BU of 7zeb by Molmil
Complex I from Ovis aries at pH9, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-30
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDP
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BU of 7zdp by Molmil
Complex I from Ovis aries at pH9, Open state
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022

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