1BNC
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THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE
Descriptor:BIOTIN CARBOXYLASE
Authors:Waldrop, G., Rayment, I., Holden, H.M.
Deposit date:1994-07-06
Release date:1995-08-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase.
Biochemistry, 33, 1994
1DV1
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STRUCTURE OF BIOTIN CARBOXYLASE (APO)
Descriptor:BIOTIN CARBOXYLASE (APO)
Authors:Thoden, J.B., Blanchard, C.Z, Holden, H.M., Waldrop, G.W
Deposit date:2000-01-19
Release date:2000-06-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1DV2
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THE STRUCTURE OF BIOTIN CARBOXYLASE, MUTANT E288K, COMPLEXED WITH ATP
Descriptor:BIOTIN CARBOXYLASE (MUTANT E288K) (E.C. 6.3.4.14) COMPLEXED WITH ATP
Authors:Thoden, J.B., Blanchard, C.Z., Holden, H.M., Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1ULZ
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CRYSTAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF PYRUVATE CARBOXYLASE
Descriptor:pyruvate carboxylase n-terminal domain (E.C.6.4.1.1)
Authors:Kondo, S., Nakajima, Y., Sugio, S., Yong-Biao, J., Sueda, S., Kondo, H.
Deposit date:2003-09-18
Release date:2004-03-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1W93
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL-COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:ACETYL-COENZYME A CARBOXYLASE (E.C.6.4.1.2)
Authors:Shen, Y., Volrath, S.L., Weatherly, S.C., Elich, T.D., Tong, L.
Deposit date:2004-10-05
Release date:2005-01-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
1W96
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL-COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH SORAPHEN A
Descriptor:ACETYL-COENZYME A CARBOXYLASE (E.C.6.4.1.2)
Authors:Shen, Y., Volrath, S.L., Weatherly, S.C., Elich, T.D., Tong, L.
Deposit date:2004-10-06
Release date:2005-01-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
2C00
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM PSEUDOMONAS AERUGINOSA IN APO FORM
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2GPS
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CRYSTAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT, E23R MUTANT, OF ACETYL-COA CARBOXYLASE FROM ESCHERICHIA COLI.
Descriptor:Biotin carboxylase (E.C.6.3.4.14, 6.4.1.2)
Authors:Shen, Y., Chou, C.Y., Chang, G.G., Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2GPW
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CRYSTAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT, F363A MUTANT, OF ACETYL-COA CARBOXYLASE FROM ESCHERICHIA COLI.
Descriptor:Biotin carboxylase (E.C.6.3.4.14)
Authors:Shen, Y., Chou, C.Y., Chang, G.G., Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2HJW
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CRYSTAL STRUCTURE OF THE BC DOMAIN OF ACC2
Descriptor:Acetyl-CoA carboxylase 2 (E.C.6.4.1.2)
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2006-07-02
Release date:2007-07-03
Modification date:2009-04-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
Proteins, 70, 2008
2J9G
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMPPNP AND ADP
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2QF7
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CRYSTAL STRUCTURE OF A COMPLETE MULTIFUNCTIONAL PYRUVATE CARBOXYLASE FROM RHIZOBIUM ETLI
Descriptor:Pyruvate carboxylase protein (E.C.6.4.1.1)
Authors:St Maurice, M., Surinya, K.H., Rayment, I.
Deposit date:2007-06-27
Release date:2007-09-04
Modification date:2012-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
2V58
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V59
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V5A
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2VQD
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM PSEUDOMONAS AERUGINOSA COMPLEXED WITH AMPCP
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I.
Deposit date:2008-03-13
Release date:2008-09-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2VR1
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH ATP ANALOG, ADPCF2P.
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14)
Authors:Mochalkin, I., Waldrop, G.L.
Deposit date:2008-03-24
Release date:2008-09-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2W6M
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMINO-OXAZOLE FRAGMENT SERIES
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6N
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH AMINO-OXAZOLE FRAGMENT SERIES
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6O
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH 4-AMINO-7,7-DIMETHYL-7,8-DIHYDRO-QUINAZOLINONE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6P
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH 5-METHYL-6-PHENYL-QUINAZOLINE-2,4-DIAMINE
Descriptor:ACETYL-COA CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6Q
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE TRIAZINE-2,4-DIAMINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W6Z
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE 3-(3-METHYL-BUT-2-ENYL)-3H-PURIN-6-YLAMINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W70
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE AMINO-THIAZOLE-PYRIMIDINE FRAGMENT
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
2W71
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E. COLI IN COMPLEX WITH THE IMIDAZOLE-PYRIMIDINE INHIBITOR
Descriptor:BIOTIN CARBOXYLASE (E.C.6.3.4.14, 6.4.1.2)
Authors:Mochalkin, I., Miller, J.R.
Deposit date:2008-12-19
Release date:2009-05-19
Modification date:2014-11-19
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009
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