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1A8M
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1a8m
TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT
Descriptor:TUMOR NECROSIS FACTOR ALPHA
Authors:Reed, C., Fu, Z.-Q., Wu, J., Xue, Y.-N., Harrison, R.W., Chen, M.-J., Weber, I.T.
Deposit date:1998-03-27
Release date:1998-06-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2.
Protein Eng., 10, 1997
1ALY
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1aly
CRYSTAL STRUCTURE OF HUMAN CD40 LIGAND
Descriptor:CD40 LIGAND
Authors:Karpusas, M., Hsu, Y.M., Thomas, D.
Deposit date:1997-06-05
Release date:1997-09-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:2 A crystal structure of an extracellular fragment of human CD40 ligand.
Structure, 3, 1995
1D2Q
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1d2q
CRYSTAL STRUCTURE OF HUMAN TRAIL
Descriptor:TNF-RELATED APOPTOSIS INDUCING LIGAND
Authors:Cha, S.-S.
Deposit date:1999-09-27
Release date:2000-02-11
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity.
Immunity, 11, 1999
1DG6
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1dg6
CRYSTAL STRUCTURE OF APO2L/TRAIL
Descriptor:APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL)
Authors:Hymowitz, S.G., O'ConnelL, M.P., Ultsch, M.H., de Vos, A.M., Kelley, R.F.
Deposit date:1999-11-23
Release date:2000-01-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL.
Biochemistry, 39, 2000
1IQA
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1iqa
CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND
Descriptor:RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND
Authors:Ito, S., Wakabayashi, K., Ubukata, O., Hayashi, S., Okada, F., Hata, T.
Deposit date:2001-07-11
Release date:2002-03-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution.
J.Biol.Chem., 277, 2002
1JH5
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1jh5
CRYSTAL STRUCTURE OF STALL-1 OF TNF FAMILY LIGAND
Descriptor:TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B
Authors:Liu, Y., Xu, L., Opalka, N., Shu, H.-B., Zhang, G.
Deposit date:2001-06-27
Release date:2002-02-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.
Cell(Cambridge,Mass.), 108, 2002
1JTZ
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1jtz
CRYSTAL STRUCTURE OF TRANCE/RANKL CYTOKINE.
Descriptor:TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11
Authors:Nelson, C.A., Fremont, D.H.
Deposit date:2001-08-23
Release date:2001-09-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity
J.Clin.Invest., 108, 2001
1KD7
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1kd7
CRYSTAL STRUCTURE OF AN EXTRACELLULAR DOMAIN FRAGMENT OF HUMAN BAFF
Descriptor:BAFF
Authors:Karpusas, M., Cachero, T.G., Qian, F., Boriack-Sjodin, A., Mullen, C., Strauch, K., Hsu, Y-M., Kalled, S.L.
Deposit date:2001-11-12
Release date:2002-11-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Extracellular Human BAFF, a TNF Family Member that Stimulates B Lymphocytes
J.Mol.Biol., 315, 2002
1KXG
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1kxg
THE 2.0 ANG RESOLUTION STRUCTURE OF BLYS, B LYMPHOCYTE STIMULATOR.
Descriptor:B lymphocyte stimulator
Authors:Oren, D.A., Li, Y., Volovik, Y., Morris, T.S., Dharia, C., Das, K., Galperina, O., Gentz, R., Arnold, E.
Deposit date:2002-01-31
Release date:2002-03-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of BLyS receptor recognition.
Nat.Struct.Biol., 9, 2002
1OSG
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1osg
COMPLEX BETWEEN BAFF AND A BR3 DERIVED PEPTIDE PRESENTED IN A BETA-HAIRPIN SCAFFOLD
Descriptor:Tumor necrosis factor ligand superfamily member 13B, BR3 derived PEPTIDE
Authors:Gordon, N.C., Pan, B., Hymowitz, S.G., Yin, J.P., Kelley, R.F., Cochran, A.G., Yan, M., Dixit, V.M., Fairbrother, W.J., Starovasnik, M.A.
Deposit date:2003-03-19
Release date:2003-05-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, 42, 2003
1OTZ
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1otz
CRYSTAL STRUCTURE OF THE BAFF-BAFF-R COMPLEX (PART I)
Descriptor:Tumor necrosis factor ligand superfamily member 13B
Authors:Kim, H.M., Yu, K.S., Lee, M.E., Shin, D.R., Kim, Y.S., Paik, S.G., Yoo, O.J., Lee, H., Lee, J.-O.
Deposit date:2003-03-23
Release date:2003-05-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
NAT.STRUCT.BIOL., 10, 2003
1RJ7
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1rj7
CRYSTAL STRUCTURE OF EDA-A1
Descriptor:Ectodysplasin A
Authors:Hymowitz, S.G., Compaan, D.M., Yan, M., Ackerly, H., Dixit, V.M., Starovasnik, M.A., de Vos, A.M.
Deposit date:2003-11-18
Release date:2003-12-09
Modification date:2011-10-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.
Structure, 11, 2003
1RJ8
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1rj8
THE CRYSTAL STRUCTURE OF TNF FAMILY MEMBER EDA-A2
Descriptor:ectodysplasin-A isoform EDA-A2
Authors:Hymowitz, S.G., Compaan, D.M., Yan, M., Ackerly, H., Dixit, V.M., Starovasnik, M.A., de Vos, A.M.
Deposit date:2003-11-18
Release date:2003-12-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Crystal Structure of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity
STRUCTURE, 11, 2003
1S55
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1s55
MOUSE RANKL STRUCTURE AT 1.9A RESOLUTION
Descriptor:Tumor necrosis factor ligand superfamily member 11
Authors:Teale, M.J., Feug, X., Chen, L., Bice, T., Meehan, E.J.
Deposit date:2004-01-19
Release date:2005-07-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Murine RANKL Extra Cellular Domain Homotrimer Structure In Space Groups P212121 And H3 At 1.9 And 2.6 Respectively
To be Published
1TNF
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1tnf
THE STRUCTURE OF TUMOR NECROSIS FACTOR-ALPHA AT 2.6 ANGSTROMS RESOLUTION. IMPLICATIONS FOR RECEPTOR BINDING
Descriptor:TUMOR NECROSIS FACTOR-ALPHA (CACHECTIN)
Authors:Eck, M.J., Sprang, S.R.
Deposit date:1989-08-25
Release date:1990-01-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.
J.Biol.Chem., 264, 1989
1U5X
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1u5x
CRYSTAL STRUCTURE OF MURINE APRIL AT PH 5.0
Descriptor:Tumor necrosis factor ligand superfamily member 13
Authors:Wallweber, H.J., Compaan, D.M., Starovasnik, M.A., Hymowitz, S.G.
Deposit date:2004-07-28
Release date:2004-10-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5Y
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1u5y
CRYSTAL STRUCTURE OF MURINE APRIL, PH 8.0
Descriptor:Tumor necrosis factor ligand superfamily member 13
Authors:Wallweber, H.J., Compaan, D.M., Starovasnik, M.A., Hymowitz, S.G.
Deposit date:2004-07-28
Release date:2004-10-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5Z
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1u5z
THE CRYSTAL STRUCTURE OF MURINE APRIL, PH 8.5
Descriptor:Tumor necrosis factor ligand superfamily member 13
Authors:Wallweber, H.J., Compaan, D.M., Starovasnik, M.A., Hymowitz, S.G.
Deposit date:2004-07-28
Release date:2004-10-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
2AZ5
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2az5
CRYSTAL STRUCTURE OF TNF-ALPHA WITH A SMALL MOLECULE INHIBITOR
Descriptor:Tumor necrosis factor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form]
Authors:He, M.M.
Deposit date:2005-09-09
Release date:2005-11-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small-molecule inhibition of TNF-alpha.
Science, 310, 2005
2E7A
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2e7a
TNF RECEPTOR SUBTYPE ONE-SELECTIVE TNF MUTANT WITH ANTAGONISTIC ACTIVITY
Descriptor:Tumor necrosis factor
Authors:Mukai, Y., Yamagata, Y., Tsutsumi, Y.
Deposit date:2007-01-09
Release date:2007-11-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist
J.Biol.Chem., 283, 2008
2HEW
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2hew
THE X-RAY CRYSTAL STRUCTURE OF MURINE OX40L
Descriptor:Tumor necrosis factor ligand superfamily member 4
Authors:Hymowitz, S.G., Compaan, D.M.
Deposit date:2006-06-22
Release date:2006-08-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
2O0O
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2o0o
CRYSTAL STRUCTURE OF TL1A
Descriptor:Crystal structure of TL1A
Authors:Jin, T.C., Kim, S., Guo, F., Howard, A.J., Zhang, Y.Z.
Deposit date:2006-11-27
Release date:2007-10-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray crystal structure of TNF ligand family member TL1A at 2.1A.
Biochem.Biophys.Res.Commun., 364, 2007
2Q1M
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2q1m
CRYSTAL STRUCTURE OF HUMAN GITRL
Descriptor:Tumor necrosis factor ligand superfamily member 18
Authors:Chattopadhyay, K., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2007-05-24
Release date:2007-11-13
Modification date:2008-12-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proc.Natl.Acad.Sci.USA, 104, 2007
2Q8O
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2q8o
CRYSTAL STRUCTURE OF MOUSE GITR LIGAND DIMER
Descriptor:GITR ligand
Authors:Zhaocai, Z., Yukiko, T.
Deposit date:2007-06-11
Release date:2007-12-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for ligand-mediated mouse GITR activation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2QDN
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2qdn
CRYSTAL STRUCTURE OF MOUSE GITRL
Descriptor:GITR ligand
Authors:Chattopadhyay, K., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2007-06-21
Release date:2008-01-01
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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