8H3V
| Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC | Descriptor: | DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. | Deposit date: | 2022-10-09 | Release date: | 2023-10-04 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
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7YHJ
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7W08
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7W07
| Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate, Space group C121. | Descriptor: | 2-methylidenebutanedioic acid, SULFATE ION, Transcriptional regulator, ... | Authors: | Sun, P.K, Wang, B, Li, X.J. | Deposit date: | 2021-11-17 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages. Nat Commun, 13, 2022
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7W06
| Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate (SeMet labeled), Space group C121. | Descriptor: | 2-methylidenebutanedioic acid, CHLORIDE ION, SULFATE ION, ... | Authors: | Sun, P.K, Wang, B, Wang, Z.X, Qi, S, Li, X.J. | Deposit date: | 2021-11-17 | Release date: | 2022-10-26 | Last modified: | 2022-11-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages. Nat Commun, 13, 2022
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7TRV
| Crystal Structure of the DNA-Binding Domain of the LysR family Transcriptional Regulator YfbA from Yersinia pestis | Descriptor: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Kim, Y, Tesar, C, Crawford, M, Chhor, G, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2022-01-31 | Release date: | 2022-02-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the DNA-Binding Domain of the LysR family Transcriptional Regulator YfbA from Yersinia pestis To Be Published
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7QAV
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7QA3
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7QA0
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7L4S
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7DWO
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7DWN
| Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator | Authors: | Wang, W.W, Wu, H, He, J.H, Yu, F. | Deposit date: | 2021-01-17 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism. Int.J.Biol.Macromol., 183, 2021
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7DMW
| Crystal structure of CcpC regulatory domain in complex with citrate from Bacillus amyloliquefaciens | Descriptor: | CITRATE ANION, CcpC | Authors: | Chen, J, Wang, L, Shang, F, Liu, W, Chen, Y, Lan, J, Bu, T, Bai, X, Xu, Y. | Deposit date: | 2020-12-08 | Release date: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Functional and structural analysis of catabolite control protein C that responds to citrate. Sci Rep, 11, 2021
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7D98
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6XTV
| FULL-LENGTH LTTR LYSG FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND EFFECTOR ARG | Descriptor: | ARGININE, Lysine export transcriptional regulatory protein LysG | Authors: | Hofmann, E, Syberg, F, Schlicker, C, Eggeling, L, Schendzielorz, G. | Deposit date: | 2020-01-16 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Engineering and application of a biosensor with focused ligand specificity. Nat Commun, 11, 2020
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6XTU
| FULL-LENGTH LTTR LYSG FROM CORYNEBACTERIUM GLUTAMICUM | Descriptor: | Lysine export transcriptional regulatory protein LysG | Authors: | Hofmann, E, Syberg, F, Schlicker, C, Eggeling, L, Schendzielorz, G. | Deposit date: | 2020-01-16 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Engineering and application of a biosensor with focused ligand specificity. Nat Commun, 11, 2020
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6M5F
| Crystal structure of HinK, a LysR family transcriptional regulator from Pseudomonas aeruginosa | Descriptor: | Probable transcriptional regulator | Authors: | Wang, Y, Lan, L, Cao, Q, Gan, J, Wang, F. | Deposit date: | 2020-03-10 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of HinK, a LysR family transcriptional regulator from Pseudomonas aeruginosa To Be Published
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6G4R
| Corynebacterium glutamicum OxyR C206S mutant, H2O2-bound | Descriptor: | 1,2-ETHANEDIOL, HYDROGEN PEROXIDE, Hydrogen peroxide-inducible genes activator, ... | Authors: | Young, D.R, Pedre, B.P, Messens, J.M. | Deposit date: | 2018-03-28 | Release date: | 2018-12-05 | Last modified: | 2018-12-19 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6G1D
| Corynebacterium glutamicum OxyR C206 mutant | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | Authors: | Young, D.R, Pedre, B.P, Messens, J.M. | Deposit date: | 2018-03-21 | Release date: | 2018-12-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.992 Å) | Cite: | Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6G1B
| Corynebacterium glutamicum OxyR, oxidized form | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, HYDROGEN PEROXIDE, ... | Authors: | Young, D.R, Pedre, B.P, Messens, J.M. | Deposit date: | 2018-03-21 | Release date: | 2018-12-05 | Last modified: | 2018-12-19 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5Z7H
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5Z72
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5Z4Y
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5YDW
| Full-length structure of HypT from Salmonella typhimuriuma (hypochlorite-specific LysR-type transcriptional regulator) | Descriptor: | Cell density-dependent motility repressor | Authors: | Jo, I, Hong, S, Ahn, J, Ha, N.C. | Deposit date: | 2017-09-15 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5Y2V
| Strcutrue of the full-length CcmR complexed with 2-OG from Synechocystis PCC6803 | Descriptor: | 2-OXOGLUTARIC ACID, PHOSPHATE ION, Rubisco operon transcriptional regulator | Authors: | Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z. | Deposit date: | 2017-07-27 | Release date: | 2017-12-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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