PDB: 69 resultsInfo pagesStatus searchChemie searchBIRD

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8R7Q	human connexin-36 gap junction channel in complex with quinine Descriptor: Gap junction delta-2 protein, Quinine Authors: Ding, X.Y, Blum, T.B, Korkhov, V.M. Deposit date: 2023-11-27 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: Structural basis of connexin-36 gap junction channel inhibition. Cell Discov, 10, 2024
8R7P	human connexin-36 gap junction channel Descriptor: Gap junction delta-2 protein Authors: Ding, X.Y, Blum, T.B, Korkhov, V.M. Deposit date: 2023-11-27 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Structural basis of connexin-36 gap junction channel inhibition. Cell Discov, 10, 2024
8QOJ	human connexin-36 gap junction channel in complex with mefloquine Descriptor: Gap junction delta-2 protein, Mefloquine Authors: Ding, X.Y, Blum, T.B, Korkhov, V.M. Deposit date: 2023-09-29 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (2.13 Å) Cite: Structural basis of connexin-36 gap junction channel inhibition. Cell Discov, 10, 2024
8QA3	Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8QA2	Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8QA1	Cryo-EM structure of Cx26 solubilised in LMNG - Hemichannel classification NFlex conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8QA0	Cryo-EM structure of Cx26 solubilised in LMNG - hemichannel classification - NConst conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8Q9Z	Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel) Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8IYG	Human neuronal gap junction channel connexin 36 Descriptor: CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, Gap junction delta-2 protein Authors: Mao, W.X, Chen, S.S. Deposit date: 2023-04-04 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Assembly mechanisms of the neuronal gap junction channel connexin 36 elucidated by Cryo-EM. Arch.Biochem.Biophys., 754, 2024
8HKP	Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry) Descriptor: Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol Authors: Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. Deposit date: 2022-11-27 Release date: 2023-03-22 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
8GNB	structure of human connexin 40.1 side-by-side decamer channel by cryoEM Descriptor: Gap junction delta-4 protein Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: structure of human connexin 40.1 side-by-side decamer channel by cryoEM To Be Published
8GN8	structure of human connexin 40.1 pentameric hemichannel by cryoEM Descriptor: Gap junction delta-4 protein Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: structure of human connexin 40.1 intercellular gap junction channel by cryoEM To Be Published
8GN7	structure of human connexin 40.1 intercellular gap junction channel by cryoEM Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Gap junction delta-4 protein, ... Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: structure of human connexin 40.1 intercellular gap junction channel by cryoEM To Be Published
7ZXT	cryo-EM structure of Connexin 32 W3S mutation hemi channel Descriptor: Gap junction beta-1 protein Authors: Qi, C, Korkhov, V.M. Deposit date: 2022-05-22 Release date: 2023-05-31 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
7ZXQ	cryo-EM structure of Connexin 32 R22G mutation hemi channel Descriptor: Gap junction beta-1 protein Authors: Qi, C, Korkhov, V.M. Deposit date: 2022-05-22 Release date: 2023-05-31 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
7ZXP	cryo-EM structure of Connexin 32 R22G mutation gap junction channel Descriptor: Gap junction beta-1 protein Authors: Qi, C, Korkhov, V.M. Deposit date: 2022-05-22 Release date: 2023-05-31 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
7ZXO	cryo-EM structure of Connexin 32 gap junction channel Descriptor: Gap junction beta-1 protein Authors: Qi, C, Korkhov, V.M. Deposit date: 2022-05-21 Release date: 2023-05-31 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
7ZXN	cryo-EM structure of Connexin 32 gap junction channel Descriptor: CHOLESTEROL, Gap junction beta-1 protein Authors: Qi, C, Korkhov, V.M. Deposit date: 2022-05-21 Release date: 2023-05-31 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
7ZXM	cryo-EM structure of Connexin 32 gap junction channel Descriptor: Gap junction beta-1 protein Authors: Qi, C, Korkhov, V.M. Deposit date: 2022-05-21 Release date: 2023-05-31 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.14 Å) Cite: Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
7Z23	Connexin43 hemi channel in nanodisc Descriptor: Gap junction alpha-1 protein Authors: Qi, C, Korkhov, M.V. Deposit date: 2022-02-25 Release date: 2023-03-08 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.98 Å) Cite: Structure of the connexin-43 gap junction channel in a putative closed state. Elife, 12, 2023
7Z22	Connexin43 gap junction channel structure in nanodisc Descriptor: Gap junction alpha-1 protein Authors: Qi, C, Korkhov, M.V. Deposit date: 2022-02-25 Release date: 2023-03-08 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Structure of the connexin-43 gap junction channel in a putative closed state. Elife, 12, 2023
7Z1T	Connexin43 gap junction channel structure in digitonin Descriptor: Gap junction alpha-1 protein Authors: Qi, C, Korkhov, M.V. Deposit date: 2022-02-25 Release date: 2023-03-08 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (2.26 Å) Cite: Structure of the connexin-43 gap junction channel in a putative closed state. Elife, 12, 2023
7XQJ	Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (PLN conformation) Descriptor: Gap junction alpha-1 protein Authors: Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. Deposit date: 2022-05-07 Release date: 2023-01-25 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (4 Å) Cite: Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
7XQI	Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (FIN conformation) Descriptor: Gap junction alpha-1 protein Authors: Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. Deposit date: 2022-05-07 Release date: 2023-01-25 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
7XQH	Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN-TM1i conformation) Descriptor: C-terminal deletion mutant of gap junction alpha-1 protein (Cx43-M257) Authors: Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. Deposit date: 2022-05-07 Release date: 2023-01-25 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023

 

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