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1BPR
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1bpr
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNAK
Authors:Wang, H., Kurochkin, A.V., Pang, Y., Hu, W., Flynn, G.C., Zuiderweg, E.R.P.
Deposit date:1998-08-11
Release date:1999-03-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.
Biochemistry, 37, 1998
1CKR
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1ckr
HIGH RESOLUTION SOLUTION STRUCTURE OF THE HEAT SHOCK COGNATE-70 KD SUBSTRATE BINDING DOMAIN OBTAINED BY MULTIDIMENSIONAL NMR TECHNIQUES
Descriptor:HEAT SHOCK SUBSTRATE BINDING DOMAIN OF HSC-70
Authors:Morshauser, R.C., Hu, W., Wang, H., Pang, Y., Flynn, G.C., Zuiderweg, E.R.P.
Deposit date:1999-04-22
Release date:1999-04-30
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70.
J.Mol.Biol., 289, 1999
1DG4
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1dg4
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK IN THE APO FORM
Descriptor:MOLECULAR CHAPERONE DNAK
Authors:Pellecchia, M., Montgomery, D.L., Stevens, S.Y., Van der Kooi, C.W., Feng, H., Gierasch, L.M., Zuiderweg, E.R.P.
Deposit date:1999-11-23
Release date:1999-12-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural insights into substrate binding by the molecular chaperone DnaK.
Nat.Struct.Biol., 7, 2000
1DKX
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1dkx
THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 SELENOMETHIONYL CRYSTALS
Descriptor:SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES)
Authors:Zhu, X., Zhao, X., Burkholder, W.F., Gragerov, A., Ogata, C.M., Gottesman, M.E., Hendrickson, W.A.
Deposit date:1996-06-03
Release date:1996-12-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
1DKY
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1dky
THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 2 NATIVE CRYSTALS
Descriptor:DNAK, PEPTIDE SUBSTRATE
Authors:Zhu, X., Zhao, X., Burkholder, W.F., Gragerov, A., Ogata, C.M., Gottesman, M.E., Hendrickson, W.A.
Deposit date:1996-06-03
Release date:1996-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
1DKZ
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1dkz
THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 NATIVE CRYSTALS
Descriptor:SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES)
Authors:Zhu, X., Zhao, X., Burkholder, W.F., Gragerov, A., Ogata, C.M., Gottesman, M.E., Hendrickson, W.A.
Deposit date:1996-06-03
Release date:1996-12-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
1Q5L
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1q5l
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK BOUND TO THE PEPTIDE NRLLLTG
Descriptor:Chaperone protein dnaK, Hypothetical 171.5 kDa helicase in NUT1-ARO2 intergenic region
Authors:Stevens, S.Y., Cai, S., Pellecchia, M., Zuiderweg, E.R.
Deposit date:2003-08-08
Release date:2003-11-04
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The solution structure of the bacterial HSP70 chaperone protein domain DnaK(393-507) in complex with the peptide NRLLLTG.
Protein Sci., 12, 2003
1U00
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1u00
HSCA SUBSTRATE BINDING DOMAIN COMPLEXED WITH THE ISCU RECOGNITION PEPTIDE ELPPVKIHC
Descriptor:Chaperone protein hscA, IscU recognition peptide
Authors:Cupp-Vickery, J.R., Peterson, J.C., Ta, D.T., Vickery, L.E.
Deposit date:2004-07-12
Release date:2004-10-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Molecular Chaperone HscA Substrate Binding Domain Complexed with the IscU Recognition Peptide ELPPVKIHC.
J.Mol.Biol., 342, 2004
1UD0
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1ud0
CRYSTAL STRUCTURE OF THE C-TERMINAL 10-KDA SUBDOMAIN OF HSC70
Descriptor:70 kDa heat-shock-like protein
Authors:Chou, C.C., Forouhar, F., Yeh, Y.H., Wang, C., Hsiao, C.D.
Deposit date:2003-04-24
Release date:2004-05-11
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Crystal structure of the C-terminal 10-kDa subdomain of Hsc70
J.BIOL.CHEM., 278, 2003
1XQS
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1xqs
CRYSTAL STRUCTURE OF THE HSPBP1 CORE DOMAIN COMPLEXED WITH THE FRAGMENT OF HSP70 ATPASE DOMAIN
Descriptor:HSPBP1 protein, Heat shock 70 kDa protein 1
Authors:Shomura, Y., Dragovic, Z., Chang, H.C., Tzvetkov, N., Young, J.C., Brodsky, J.L., Guerriero, V., Hartl, F.U., Bracher, A.
Deposit date:2004-10-13
Release date:2005-03-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Regulation of Hsp70 Function by HspBP1; Structural Analysis Reveals an Alternate Mechanism for Hsp70 Nucleotide Exchange
Mol.Cell, 17, 2005
2BPR
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2bpr
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES
Descriptor:DNAK
Authors:Wang, H., Kurochkin, A.V., Pang, Y., Hu, W., Flynn, G.C., Zuiderweg, E.R.P.
Deposit date:1998-08-11
Release date:1999-03-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.
Biochemistry, 37, 1998
2KHO
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2kho
NMR-RDC / XRAY STRUCTURE OF E. COLI HSP70 (DNAK) CHAPERONE (1-605) COMPLEXED WITH ADP AND SUBSTRATE
Descriptor:Heat shock protein 70
Authors:Zuiderweg, E.R.P., Bertelsen, E.B.
Deposit date:2009-04-10
Release date:2009-05-12
Modification date:2012-05-16
Method:SOLUTION NMR
Cite:Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate.
Proc.Natl.Acad.Sci.USA, 106, 2009
2LMG
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2lmg
SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN (537-610) OF HUMAN HEAT SHOCK PROTEIN 70
Descriptor:Heat shock 70 kDa protein 1A/1B
Authors:Zhou, C., Gao, X., Wu, M., Hu, H.
Deposit date:2011-12-01
Release date:2012-01-11
Method:SOLUTION NMR
Cite:The C-terminal helices of HSP70 are essential for HSJ1a J-domain binding and ATPase activation
J.Biol.Chem., 2012
2OP6
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2op6
PEPTIDE-BINDING DOMAIN OF HEAT SHOCK 70 KDA PROTEIN D PRECURSOR FROM C.ELEGANS
Descriptor:Heat shock 70 kDa protein D
Authors:Osipiuk, J., Duggan, E., Gu, M., Voisine, C., Morimoto, R.I., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-01-26
Release date:2007-02-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray structure of peptide-binding domain of Heat shock 70 kDa protein D precursor from C.elegans
To be Published
2P32
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2p32
CRYSTAL STRUCTURE OF THE C-TERMINAL 10 KDA SUBDOMAIN FROM C. ELEGANS HSP70
Descriptor:Heat shock 70 kDa protein A
Authors:Worrall, L.J., Walkinshaw, M.D.
Deposit date:2007-03-08
Release date:2007-04-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the C-terminal three-helix bundle subdomain of C. elegans Hsp70.
Biochem.Biophys.Res.Commun., 357, 2007
2QXL
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2qxl
CRYSTAL STRUCTURE ANALYSIS OF SSE1, A YEAST HSP110
Descriptor:Heat shock protein homolog SSE1
Authors:Hendrickson, W.A., Liu, Q.
Deposit date:2007-08-12
Release date:2007-10-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Insights into hsp70 chaperone activity from a crystal structure of the yeast hsp110 Sse1.
Cell(Cambridge,Mass.), 131, 2007
3DOB
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3dob
PEPTIDE-BINDING DOMAIN OF HEAT SHOCK 70 KDA PROTEIN F44E5.5 FROM C.ELEGANS.
Descriptor:Heat shock 70 kDa protein F44E5.5
Authors:Osipiuk, J., Hatzos, C., Gu, M., Zhang, R., Voisine, C., Morimoto, R.I., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-07-03
Release date:2008-07-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:X-ray crystal structure of Peptide-binding domain of Heat shock 70 kDa protein F44E5.5 from C.elegans.
To be Published
3DPO
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3dpo
CRYSTAL STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF E. COLI DNAK IN COMPLEX WITH A SHORT PYRRHOCORICIN-DERIVED INHIBITOR PEPTIDE
Descriptor:Chaperone protein dnaK, inhibitor peptide
Authors:Roujeinikova, A.
Deposit date:2008-07-09
Release date:2009-03-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies
J.Bacteriol., 191, 2009
3DPP
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3dpp
CRYSTAL STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF E. COLI DNAK IN COMPLEX WITH A LONG PYRRHOCORICIN-DERIVED INHIBITOR PEPTIDE (FORM A)
Descriptor:Chaperone protein dnaK, inhibitor peptide
Authors:Roujeinikova, A.
Deposit date:2008-07-09
Release date:2009-03-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.
J.Bacteriol., 191, 2009
3DPQ
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3dpq
CRYSTAL STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF E. COLI DNAK IN COMPLEX WITH A LONG PYRRHOCORICIN-DERIVED INHIBITOR PEPTIDE (FORM B)
Descriptor:Chaperone protein dnaK, inhibitor peptide
Authors:Roujeinikova, A.
Deposit date:2008-07-09
Release date:2009-03-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.
J.Bacteriol., 191, 2009
3DQG
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3dqg
PEPTIDE-BINDING DOMAIN OF HEAT SHOCK 70 KDA PROTEIN F, MITOCHONDRIAL PRECURSOR, FROM CAENORHABDITIS ELEGANS.
Descriptor:Heat shock 70 kDa protein F
Authors:Osipiuk, J., Mulligan, R., Gu, M., Voisine, C., Morimoto, R.I., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-07-09
Release date:2008-07-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:X-ray crystal structure of peptide-binding domain of heat shock 70 kDa protein F, mitochondrial precursor, from Caenorhabditis elegans.
To be Published
3GDQ
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3gdq
CRYSTAL STRUCTURE OF THE HUMAN 70KDA HEAT SHOCK PROTEIN 1-LIKE ATPASE DOMAIN IN COMPLEX WITH ADP AND INORGANIC PHOSPHATE
Descriptor:Heat shock 70 kDa protein 1-like
Authors:Wisniewska, M., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Schutz, P., Siponen, M., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Schueler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-02-24
Release date:2009-04-14
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
3H0X
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3h0x
CRYSTAL STRUCTURE OF PEPTIDE-BINDING DOMAIN OF KAR2 PROTEIN FROM SACCHAROMYCES CEREVISIAE
Descriptor:78 kDa glucose-regulated protein homolog
Authors:Osipiuk, J., Bigelow, L., Gu, M., Sahi, C., Craig, E.A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-04-10
Release date:2009-04-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:X-ray crystal structure of peptide-binding domain of Kar2 protein from Saccharomyces cerevisiae.
To be Published
3JXU
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3jxu
CRYSTAL STRUCTURE OF THE HUMAN 70KDA HEAT SHOCK PROTEIN 1A (HSP70-1) ATPASE DOMAIN IN COMPLEX WITH ADP AND INORGANIC PHOSPHATE
Descriptor:Heat shock 70 kDa protein 1
Authors:Wisniewska, M.M., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-09-21
Release date:2009-10-20
Modification date:2010-02-02
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
3KVG
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3kvg
CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM CRYPTOSPORIDIUM PARVUM IN COMPLEX WITH AMPPNP
Descriptor:Heat shock 70 (HSP70) protein
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Lew, J., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2009-11-30
Release date:2010-01-19
Modification date:2010-03-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP
To be Published
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