PDB: 13 resultsInfo pagesStatus searchChemie searchBIRD

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8BY6	Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. Deposit date: 2022-12-12 Release date: 2024-01-24 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (3.19 Å) Cite: Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
6D0Y	X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex Descriptor: MAGNESIUM ION, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Gleghorn, M.L, Maquat, L.E. Deposit date: 2018-04-11 Release date: 2018-04-25 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.676 Å) Cite: Transcriptional coactivator PGC-1 alpha contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes Dev., 32, 2018
8PNT	Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. Deposit date: 2023-07-01 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
8PMP	Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. Deposit date: 2023-06-29 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.43 Å) Cite: Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
5OO6	Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Cusack, S, Schulze, W.M. Deposit date: 2017-08-06 Release date: 2017-11-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2. Nat Commun, 8, 2017
5OOB	COMPLEX OF HUMAN NUCLEAR CAP-BINDING COMPLEX WITH M7GTP AND NELF-E C-TERMINAL PEPTIDE Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Negative elongation factor E, Nuclear cap-binding protein subunit 1, ... Authors: Cusack, S, Schulze, W.M. Deposit date: 2017-08-07 Release date: 2017-11-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2. Nat Commun, 8, 2017
3FEY	Crystal structure of the CBC-importin alpha complex. Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 Authors: Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. Deposit date: 2008-12-01 Release date: 2009-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
3FEX	Crystal structure of the CBC-importin alpha complex. Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 Authors: Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. Deposit date: 2008-12-01 Release date: 2009-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.549 Å) Cite: The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
6N7P	S. cerevisiae spliceosomal E complex (UBC4) Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, Nuclear cap-binding protein complex subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Liu, S, Li, X, Zhou, Z.H, Zhao, R. Deposit date: 2018-11-27 Release date: 2019-09-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: A unified mechanism for intron and exon definition and back-splicing. Nature, 573, 2019
7ABG	Human pre-Bact-1 spliceosome Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-07 Release date: 2020-12-23 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (7.8 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
3UKZ	Mouse importin alpha: mouse CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKY	Mouse importin alpha: yeast CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UL0	Mouse importin alpha: mouse CBP80Y8D cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012