6CME
| Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2 | Descriptor: | LIM/homeobox protein Lhx4,Insulin gene enhancer protein ISL-2, ZINC ION | Authors: | Stokes, P.H, Silva, A, Guss, J.M, Matthews, J.M. | Deposit date: | 2018-03-04 | Release date: | 2019-04-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Mutation in a flexible linker modulates binding affinity for modular complexes. Proteins, 87, 2019
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5HOD
| Structure of LHX4 transcription factor complexed with DNA | Descriptor: | DNA (5'-D(P*AP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*GP*TP*AP*AP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*TP*TP*AP*CP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*T)-3'), LIM/homeobox protein Lhx4 | Authors: | Morgunova, E, Yin, Y, Popov, A, Taipale, J. | Deposit date: | 2016-01-19 | Release date: | 2017-02-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.682 Å) | Cite: | Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
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3MMK
| The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification | Descriptor: | CHLORIDE ION, Fusion of LIM/homeobox protein Lhx4, linker, ... | Authors: | Gadd, M.S, Langley, D.B, Guss, J.M, Matthews, J.M. | Deposit date: | 2010-04-20 | Release date: | 2011-07-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.157 Å) | Cite: | The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification. J.Biol.Chem., 2011
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