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5JH5
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BU of 5jh5 by Molmil
Structural Basis for the Hierarchical Assembly of the Core of PRC1.1
Descriptor: BCL-6 corepressor-like protein 1, Lysine-specific demethylase 2B, Polycomb group RING finger protein 1, ...
Authors:Wong, S.J, Taylor, A.B, Hart, P.J, Kim, C.A.
Deposit date:2016-04-20
Release date:2016-09-14
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1.
Structure, 24, 2016
8HCU
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BU of 8hcu by Molmil
Crystal structure of BCOR/PCGF1/KDM2B complex
Descriptor: ACETIC ACID, BCL-6 corepressor, Polycomb group RING finger protein 1, ...
Authors:Shen, F, Chen, R, Xu, J, Liu, J.
Deposit date:2022-11-03
Release date:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of BCOR/PCGF1/KDM2B complex
to be published
4O64
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BU of 4o64 by Molmil
Zinc fingers of KDM2B
Descriptor: Lysine-specific demethylase 2B, UNKNOWN ATOM OR ION, ZINC ION
Authors:Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-20
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
6BVA
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BU of 6bva by Molmil
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
Descriptor: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-12
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
7UV9
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BU of 7uv9 by Molmil
KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate
Descriptor: DNA (185-MER), FE (III) ION, Histone H2A type 1, ...
Authors:Spangler, C.J, Skrajna, A, Foley, C.A, Budziszewski, G.R, Azzam, D.N, James, L.I, Frye, S.V, McGinty, R.K.
Deposit date:2022-04-29
Release date:2023-02-22
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
7UVA
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BU of 7uva by Molmil
Crystal structure of KDM2A histone demethylase catalytic domain in complex with an H3C36 peptide modified by UNC8015
Descriptor: FE (III) ION, Histone H3.2, Lysine-specific demethylase 2A, ...
Authors:Budziszewski, G.R, Azzam, D.N, Spangler, C.J, Skrajna, A, Foley, C.A, James, L.I, Frye, S.V, McGinty, R.K.
Deposit date:2022-04-29
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
5K4L
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BU of 5k4l by Molmil
Crystal structure of KDM5A in complex with a naphthyridone inhibitor
Descriptor: Lysine-specific demethylase 5A, NICKEL (II) ION, Unknown Peptide, ...
Authors:Kiefer, J.R, Vinogradova, M.V.
Deposit date:2016-05-20
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (3.179 Å)
Cite:Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016

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