PDB: 9 resultsInfo pagesStatus searchChemie searchBIRD

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5FWJ	Crystal structure of human JARID1C in complex with KDM5-C49 Descriptor: 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, HISTONE DEMETHYLASE JARID1C, MAGNESIUM ION, ... Authors: Srikannathasan, V, Szykowska, A, Strain-Damerell, C, Kopec, J, Nowak, R, Gileadi, C, Johansson, C, Kupinska, K, Burgess-Brown, N.A, Shrestha, L, Dong, W, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K, Oppermann, U. Deposit date: 2016-02-17 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol., 12, 2016
5E6H	A Linked Jumonji Domain of the KDM5A Lysine Demethylase Descriptor: 2-OXOGLUTARIC ACID, GLYCEROL, Lysine-specific demethylase 5A, ... Authors: Horton, J.R, Cheng, X. Deposit date: 2015-10-09 Release date: 2015-12-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.238 Å) Cite: Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases. J.Biol.Chem., 291, 2016
5FP8	Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- ylmethylaminopyridine-4-carboxylic acid Descriptor: 3-[(4-methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acid, COBALT (II) ION, LYSINE-SPECIFIC DEMETHYLASE 4D, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-01-27 Last modified: 2016-03-09 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem., 59, 2016
5FPB	Crystal structure of human KDM4D in complex with 2-1H-pyrazol-4-yloxy- 3H,4H-pyrido-3,4-d-pyrimidin-4-one Descriptor: 2-(1H-pyrazol-4-yloxy)-3H-pyrido[3,4-d]pyrimidin-4-one, COBALT (II) ION, LYSINE-SPECIFIC DEMETHYLASE 4D, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-01-27 Last modified: 2016-03-09 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem., 59, 2016
5FP4	Crystal structure of human KDM4D in complex with 3-(4- phenylbutanamido)pyridine-4-carboxylic acid Descriptor: 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid, FE (II) ION, GLYCEROL, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-01-27 Last modified: 2016-03-09 Method: X-RAY DIFFRACTION (2 Å) Cite: Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem., 59, 2016
5FP7	Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- yl methylaminopyridine-4-carboxylic acid Descriptor: 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid, FE (II) ION, GLYCEROL, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-11-09 Last modified: 2019-01-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives. J. Med. Chem., 59, 2016
5FP3	Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases Descriptor: 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid, BICINE, COBALT (II) ION, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-01-27 Last modified: 2019-10-30 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem., 59, 2016
5FP9	Crystal structure of human KDM4D in complex with 3-aminopyridine-4- carboxylic acid Descriptor: 3-AMINOPYRIDINE-4-CARBOXYLIC ACID, COBALT (II) ION, GLYCEROL, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-01-27 Last modified: 2016-03-09 Method: X-RAY DIFFRACTION (2 Å) Cite: Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem., 59, 2016
5FPA	Crystal structure of human KDM4D in complex with 3H,4H-pyrido-3,4-d- pyrimidin-4-one Descriptor: 3H-pyrido[3,4-d]pyrimidin-4-one, COBALT (II) ION, LYSINE-SPECIFIC DEMETHYLASE 4D, ... Authors: Chung, C. Deposit date: 2015-11-27 Release date: 2016-01-27 Last modified: 2016-03-09 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives. J.Med.Chem., 59, 2016